ArticleEpidemiology (Cambridge, Mass.)2018
Vulnerability to the Cardiovascular Effects of Ambient Heat in Six US Cities: Results from the Multi-Ethnic Study of Atherosclerosis (MESA).
Article in Epidemiology (Cambridge, Mass.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Association between ambient temperature and blood pressure in hypertensive adults in Bogor City, Indonesia: a 6-year longitudinal cohort study.Osong public health and research perspectives · 2026Article
- Heat-health messaging in Canada: A review and content analysis of public health authority webpages and resources.Public health in practice (Oxford, England) · 2025Article
- Associations of long-term exposure to temperature with coronary artery calcification risk among middle-aged adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study.The Science of the total environment · 2025Article
- Structural and social determinants of health: The multi-ethnic study of atherosclerosis.PloS one · 2024Article
- Climatic influences on cardiovascular diseases.World journal of cardiology · 2022Review
- Assessing proximate intermediates between ambient temperature, hospital admissions, and mortality in hemodialysis patients.Environmental research · 2022Article
- Parental age and birth defects: a sibling study.European journal of epidemiology · 2021Article
- The effect of ambient temperature on blood pressure of patients undergoing hemodialysis in the Pantanal-Brazil.Heliyon · 2021Article
- Estimating the Health-Related Costs of 10 Climate-Sensitive U.S. Events During 2012.GeoHealth · 2019Article
- Association of Extreme Heat Events With Hospital Admission or Mortality Among Patients With End-Stage Renal Disease.JAMA network open · 2019Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundWith climate change, temperatures are increasing. Heat-associated health events disproportionately affect certain subpopulations. However, prior research has often lacked information on individual-level health and air conditioning and neighborhood stressors/protections.
objectivesTo assess whether (1) heat (2-day mean temperature above local 75th percentiles) is associated with increased heart rate and decreased blood pressure, controlling for age, time, season, daily ozone, and daily particulate matter (PM2.5) and (2) associations differ by antihypertensive medication use, renal function, fasting glucose, emotional support, air conditioning ownership and use, normalized difference vegetation index, neighborhood safety, and residence- specific oxides of nitrogen and PM2.5.
methodsHealth and behavioral characteristics were obtained repeatedly on participants of the Multi-Ethnic Study of Atherosclerosis in six US sites (2000-2010). These were linked with airport temperature, air quality, and satellite- and survey-derived neighborhood characteristics. We used a fixed-effects design, regressing health outcomes on linear temperature splines with knots at the 75th percentiles, interaction terms for each characteristic, and adjustment for month of year, age, PM2.5, and ozone.
resultsOverall, heat was not associated with heart rate. However, for a 2°C increase in heat, systolic blood pressure decreased by 1.1 mmHg (95% CI = -1.6, -0.6) and diastolic blood pressure by 0.3 mmHg (95% CI = -0.6, -0.1). Among nonusers of antihypertensive medications, heat-associated decreases in SBP were 2.1 mmHg greater among individuals with central air conditioning versus those without. Confidence intervals around the remaining modifiers were wide after multiple-comparisons corrections or sensitivity analyses.
conclusionsOutdoor heat is associated with decreasing blood pressure, and cardiovascular vulnerability may vary primarily by ownership of central air conditioning.
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