Evidence map›Paper›PMID 30113214›Full record

ArticleFuture microbiology2018

Challenges in identifying antibiotic resistance targets for point-of-care diagnostics in general practice.

Konstantinos Mitsakakis, Wendy E Kaman, Gijs Elshout, Mara Specht, John P Hays

Abstract read
In one paragraph

Article in Future microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Molecular Insights into Carbapenem Resistance inInternational journal of molecular sciences · 2026
    Review
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Enabling appropriate use of antibiotics: review of European Union procedures of harmonising product information, 2007 to 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Review
  15. Point-of-Care Testing for Pharyngitis in the Pharmacy.Antibiotics (Basel, Switzerland) · 2020
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Konstantinos MitsakakisHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Wendy E KamanDepartment of Medical Microbiology & Infectious Diseases, Erasmus University Medical Centre Rotterdam (Erasmus MC), Wytemaweg 80, 3015 CN, Rotterdam, the Netherlands.
Gijs ElshoutDepartment of General Practice, Erasmus University Medical Centre Rotterdam (Erasmus MC), Wytemaweg 80, 3015 CN, Rotterdam, the Netherlands.
Mara SpechtHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
John P HaysDepartment of Medical Microbiology & Infectious Diseases, Erasmus University Medical Centre Rotterdam (Erasmus MC), Wytemaweg 80, 3015 CN, Rotterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

General practitioners stand at the front line of healthcare provision and have a pivotal role in the fight against increasing antibiotic resistance. In this respect, targeted antibiotic prescribing by general practitioners would help reduce the unnecessary use of antibiotics, leading to reduced treatment failures, fewer side-effects for patients and a reduction in the (global) spread of antibiotic resistances. Current 'gold standard' antibiotic resistance detection strategies tend to be slow, taking up to 48 h to obtain a result, although the implementation of point-of-care testing by general practitioners could help achieve the goal of targeted antibiotic prescribing practices. However, deciding on which antibiotic resistances to include in a point-of-care diagnostic is not a trivial task, as outlined in this publication.

Indexed as

Drug Resistance, MicrobialAnti-Bacterial AgentsDiagnostic Tests, RoutineGeneral PracticeHumansInappropriate PrescribingMicrobiotaPhysician-Patient RelationsPoint-of-Care SystemsPoint-of-Care TestingAnti-Bacterial Agentsantibiotic resistancegeneral practicepoint-of-care diagnostics

Identifiers

PMID30113214
PMCPMC6190172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.