Evidence map›Paper›PMID 30112975›Full record

ReviewPerfusion2019

Left ventricular unloading during veno-arterial ECMO: a review of percutaneous and surgical unloading interventions.

Dirk W Donker, Daniel Brodie, José P S Henriques, Michael Broomé

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Perfusion, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06766006 (A Multicentric Left Ventricular Venting Strategy Comparison in Patients Receiving Venoarterial Extracorporeal Life Support), which is not on this map. Cited by 74 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06766006 recruitingnot on this mapstarted 2024, after this paper: background citation

A Multicentric Left Ventricular Venting Strategy Comparison in Patients Receiving Venoarterial Extracorporeal Life Support

TypeobservationalSponsorMaastricht University Medical CenterRan2024 to 2026Enrolled500ConditionsShock, Cardiogenic, Cardiac Arrest, Extracorporeal Membrane Oxygenation ComplicationArmsVenoarterial extracorporeal life support (VA ECLS) implant
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 2 syntheses or guidelines pooled it, 165 citations in OpenAlex.

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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Dirk W Donker1 Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0001-6496-2768
Daniel Brodie2 Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University College of Physicians and Surgeons/New York-Presbyterian Hospital, New York, NY, USA.
José P S Henriques3 Department of Cardiology, Academic Medical Center, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Michael Broomé4 ECMO Department, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0002-8987-9909
Amsterdam UMC Location University of Amsterdam · NLKarolinska University Hospital · SENewYork–Presbyterian Hospital · USUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short-term mechanical support by veno-arterial extracorporeal membrane oxygenation (VA ECMO) is more and more applied in patients with severe cardiogenic shock. A major shortcoming of VA ECMO is its variable, but inherent increase of left ventricular (LV) mechanical load, which may aggravate pulmonary edema and hamper cardiac recovery. In order to mitigate these negative sequelae of VA ECMO, different adjunct LV unloading interventions have gained a broad interest in recent years. Here, we review the whole spectrum of percutaneous and surgical techniques combined with VA ECMO reported to date.

Indexed as

Extracorporeal Membrane OxygenationHeart VentriclesHumansShock, Cardiogeniccardiogenic shockcardiovascular modelingcomputer simulationleft ventricular unloadingveno-arterial extracorporeal membrane oxygenation (VA ECMO)

Identifiers

PMID30112975
PMCPMC6378398
OpenAlexW2887179887

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.