Evidence map›Paper›PMID 30112727›Full record

ArticleMolecular imaging and biology2019

Site-Specific Labeling of F-18 Proteins Using a Supplemented Cell-Free Protein Synthesis System and O-2-[

Ai Yanai, Ryuichi Harada, Ren Iwata, Takeo Yoshikawa, Yoichi Ishikawa, Shozo Furumoto, Takanori Ishida, Kazuhiko Yanai

Abstract read
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In one paragraph

Article in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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  7. Synthesis of a novelEJNMMI research · 2020
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  8. Review
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  10. PET imaging of aThe British journal of radiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ai YanaiDepartment of Surgical Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ryuichi HaradaDepartment of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan. dragon1@med.tohoku.ac.jp.ORCID 0000-0001-8538-8814
Ren IwataCyclotron and Radioisotope Center (CYRIC), Tohoku University, Sendai, Japan.
Takeo YoshikawaDepartment of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yoichi IshikawaCyclotron and Radioisotope Center (CYRIC), Tohoku University, Sendai, Japan.
Shozo FurumotoCyclotron and Radioisotope Center (CYRIC), Tohoku University, Sendai, Japan.
Takanori IshidaDepartment of Surgical Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kazuhiko YanaiDepartment of Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Tohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough a preparation method for F-18-labeled proteins that used a cell-free translation system and 4-[ PROCEDURES: [

results[

conclusionThe method proposed in this study might be useful for preparing proteins with F-18 and molecular imaging in the preclinical development.

Indexed as

Protein BiosynthesisStaining and LabelingAmino Acid SequenceAmino Acyl-tRNA SynthetasesAnimalsCell-Free SystemCell Line, TumorFemaleFluorine RadioisotopesHEK293 CellsHumansInterleukin-8Mice, SCIDProteinsRecombinant Fusion ProteinsRNA, Transfer(18F)fluoroethyltyrosineAmino Acyl-tRNA SynthetasesFluorine-18Fluorine RadioisotopesInterleukin-8O-(2-fluoroethyl)tyrosineProteinsRecombinant Fusion ProteinsRNA, TransferTyrosine[18F]FETAffibodyCell-free protein synthesisEngineered orthogonal aminoacyl-tRNA synthetase

Identifiers

PMID30112727
OpenAlexW2885273289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.