ArticleLangenbeck's archives of surgery2018
The impact of major extended donor criteria on graft failure and patient mortality after liver transplantation.
Article in Langenbeck's archives of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Evaluation of the Safety Threshold for Allograft Macrovesicular Steatosis in Cadaveric Liver Transplantation.Frontiers in physiology · 2019Pooled it
- Bone marrow mesenchymal stem cells alleviate liver fibrosis after rat liver transplantation through JAK1/STAT5 pathway.Stem cell research & therapy · 2025Article
- Intraoperative Hyperspectral Imaging Predicts Early Allograft Dysfunction and Overall Survival in Liver Transplantation.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- LiverColor: An Artificial Intelligence Platform for Liver Graft Assessment.Diagnostics (Basel, Switzerland) · 2024Article
- Cold ischemia time in liver transplantation: An overview.World journal of hepatology · 2024Article
- L-GrAFTJournal of clinical and translational hepatology · 2024Article
- Application of extended criteria donor grafts in liver transplantation for acute-on-chronic liver failure: A retrospective cohort study.World journal of gastroenterology · 2023Article
- Article
- Hyperspectral Imaging for Viability Assessment of Human Liver Allografts During Normothermic Machine Perfusion.Transplantation direct · 2022Article
- Machine Perfusion for Extended Criteria Donor Livers: What Challenges Remain?Journal of clinical medicine · 2022Review
- Prognostic role of selection criteria for liver transplantation in patients with hepatocellular carcinoma: a network meta-analysis.BJS open · 2022Article
- Post-Transplantation Cytomegalovirus Infection Interplays With the Development of Anastomotic Biliary Strictures After Liver Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
- Development of a Novel Prognostic Nomogram for High Model for End-Stage Liver Disease Score Recipients Following Deceased Donor Liver Transplantation.Frontiers in medicine · 2022Article
- Noninvasive assessment of steatosis and viability of cold-stored human liver grafts by MRI.Magnetic resonance in medicine · 2021Article
- Liver Transplantation With Grafts From Super Obese Donors.Transplantation direct · 2021Article
- Prediction of Graft Survival Post-liver Transplantation by L-GrAFT Risk Score Model, EASE Score, MEAF Scoring, and EAD.Frontiers in surgery · 2021Article
- First Preliminary Experience with Preservation of Liver Grafts from Extended-Criteria Donors by Normothermic Machine Perfusion in Asia.Annals of transplantation · 2020Article
- The Differential Influence of Cold Ischemia Time on Outcome After Liver Transplantation for Different Indications-Who Is at Risk? A Collaborative Transplant Study Report.Frontiers in immunology · 2020Article
- The Graz Liver Allocation Strategy-Impact of Extended Criteria Grafts on Outcome Considering Immunological Aspects.Frontiers in immunology · 2020Article
- Liver Grafts with Major Extended Donor Criteria May Expand the Organ Pool for Patients with Hepatocellular Carcinoma.Journal of clinical medicine · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNumerous extended donor criteria (EDC) have been identified in liver transplantation (LT), but different EDC have different impacts on graft and patient survival. This study aimed to identify major EDC (maEDC) that were best able to predict the outcome after LT and to examine the plausibility of an allocation algorithm based on these criteria.
methodsAll consecutive LTs between 12/2006 and 03/2014 were included (n = 611). We analyzed the following EDC: donor age > 65 years, body mass index > 30, malignancy and drug abuse history, intensive care unit stay/ventilation > 7 days, aminotransferases > 3 times normal, serum bilirubin > 3 mg/dL, serum Na
resultsBPS > 40%, donor age > 65 years, and CIT > 14 h (all p < 0.05) were independent predictors of graft failure and patient mortality and increased PNF, 30-day, 90-day, 1-year, and 3-year graft failure rates. Three-year graft and patient survival decreased in recipients of ≥ 1 maEDC grafts (all p < 0.05) and LT of high-risk grafts into high-risk recipients yielded worse outcomes compared with other groups.
conclusionDonor age > 65 years, BPS > 40%, and CIT > 14 h are major EDC that decrease short and 3-year graft survival, and 3-year patient survival. An allocation algorithm based on maEDC and labMELD is therefore plausible.
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