Evidence map›Paper›PMID 30112396›Full record

ArticleBioMed research international2018

Determine the Role of FSH Receptor Binding Inhibitor in Regulating Ovarian Follicles Development and Expression of FSHR and ER

Luju Lai, Xiaoyun Shen, Haoqin Liang, Yingying Deng, Zhuandi Gong, Suocheng Wei

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luju Lai *College of Life Science and Engineering, Northwest Minzu University, Lanzhou, Gansu 730030, China.
Xiaoyun Shen *State Engineering Technology Institute for Karst Desertification Control, Guizhou Normal University, Guiyang, Guizhou 550001, China.
Haoqin LiangCollege of Life Science and Engineering, Northwest Minzu University, Lanzhou, Gansu 730030, China.
Yingying DengCollege of Life Science and Engineering, Northwest Minzu University, Lanzhou, Gansu 730030, China.
Zhuandi GongMedicine College, Northwest Minzu University, Lanzhou, Gansu 730030, China.
Suocheng WeiCollege of Life Science and Engineering, Northwest Minzu University, Lanzhou, Gansu 730030, China.ORCID 0000-0002-1480-1832
Minzu University of China · CNSouthwest University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mice of FRBI-1, FRBI-2, and FRBI-3 groups were intramuscularly injected with 20, 30, and 40mg/kg, respectively, for five consecutive days. Ovarian weights of three FRBI groups were reduced in comparison with FSH group. Ovarian cortex thicknesses (OCT) of the FRBI-3 group were less than that of the FSH group (P<0.05). As compared to FSH group, there were fewer numbers of secondary follicles (SFs) and mature follicles (MF) on the ovaries of FRBI-treated mice numbers of primary follicles (PFs) and SFs also decreased. In FRBI-3 mice, we found that the primordial follicles (POF) were scarcer, the follicles developed poorly, and granulosa cells became apoptosis. SF numbers of FRBI-2 and FRBI-3 groups were less than that of the FSH group on day 20 (P<0.05). Maximum longitudinal diameter (MLD) and transverse diameter (MTD) of three FRBI groups became decreased during the experiment. MLD and MTD of the FRBI-3 group were smaller than FSH group. Levels of FSHR mRNA and protein were less than that of CG and FSH group (P<0.05). ER

Indexed as

AnimalsEstradiolEstrogen Receptor alphaFemaleFollicle Stimulating HormoneMiceOvarian FollicleOvaryReceptors, FSHEstradiolEstrogen Receptor alphaFollicle Stimulating HormoneReceptors, FSH

Identifiers

PMID30112396
PMCPMC6077528
OpenAlexW2876286898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.