Evidence map›Paper›PMID 30112379›Full record

ArticleBioMed research international2018

The Impact of Artesunate-Amodiaquine on Schistosoma mansoni Infection among Children Infected by Plasmodium in Rural Area of Lemfu, Kongo Central, Democratic Republic of the Congo.

Kennedy Makola Mbanzulu, Josué Kikana Zanga, Jean Pierre Kambala Mukendi, Felly Mbaya Ntita, Junior Rika Matangila, Hypolite Mavoko Muhindo, Sylvain Mpoyi Wa Mpoyi, Michel Ntetani Aloni, Roger Wumba

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Essential Oils as Novel Anthelmintic Drug Candidates.Molecules (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kennedy Makola MbanzuluDepartment of Tropical Medicine, Infectious and Parasitic Diseases, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.ORCID 0000-0003-2491-3907
Josué Kikana ZangaDepartment of Tropical Medicine, Infectious and Parasitic Diseases, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jean Pierre Kambala MukendiDepartment of Tropical Medicine, Infectious and Parasitic Diseases, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.ORCID 0000-0002-8383-6246
Felly Mbaya NtitaDepartment of Tropical Medicine, Infectious and Parasitic Diseases, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Junior Rika MatangilaDepartment of Tropical Medicine, Infectious and Parasitic Diseases, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Hypolite Mavoko MuhindoDepartment of Tropical Medicine, Infectious and Parasitic Diseases, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Sylvain Mpoyi Wa MpoyiNational Program of Neglected Tropical Diseases, Public Health Ministry, Democratic Republic of the Congo.
Michel Ntetani AloniDepartment of Pediatrics, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.ORCID 0000-0002-7479-1170
Roger WumbaDepartment of Tropical Medicine, Infectious and Parasitic Diseases, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
University of Kinshasa · CDMinistry of Public Health · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria and schistosomiasis remain life-threatening public health problems in sub-Saharan Africa. The infection pattern related to age indicates that preschool and school-age children are at the highest risk of malaria and schistosomiasis. Both parasitic infections, separately or combined, may have negative impacts on the haemoglobin concentration levels. The existing data revealed that artemisinin derivatives commonly used to cure malaria present also in antischistosomal activities. The current study investigated the impact of Artesunate-Amodiaquine (AS-AQ) on schistosomiasis when administered to treat malaria in rural area of Lemfu, DRC. METHODOLOGY: A prospective longitudinal study including 171 coinfected children screened for anaemia,

resultsOne hundred and twenty-five (74.4%) out of 168 coinfected children treated and present during the assessment were found stool negative for S.

conclusionThe AS-AQ commonly used against Plasmodium allowed curing

Indexed as

AdolescentAmodiaquineAnimalsAntimalarialsArtesunateChildChild, PreschoolDemocratic Republic of the CongoFemaleHumansMalaria, FalciparumMalePlasmodiumProspective StudiesRural PopulationSchistosoma mansoniAmodiaquineAntimalarialsArtesunate

Identifiers

PMID30112379
PMCPMC6077572
OpenAlexW2884780415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.