ArticleInternational journal of nephrology2018
Projecting the Burden of Chronic Kidney Disease in a Developed Country and Its Implications on Public Health.
Article in International journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Early retinal microvascular abnormalities in patients with chronic kidney disease.Microcirculation (New York, N.Y. : 1994) · 2019Trial
- Thermomechanical Tailoring of a DLP-Printable Shape Memory Polyurethane for Vascular Graft Applications.Materials (Basel, Switzerland) · 2026Article
- Linking Salivary Calbindin-D28k to Oral Health Outcomes in Chronic Kidney Disease.European journal of dentistry · 2026Article
- Association Between Chronic Kidney Disease and Glaucoma: Results From the Lifelines Cohort Study and UK Biobank.Investigative ophthalmology & visual science · 2025Article
- Disparities in ethnicity and metabolic disease burden in referrals to nephrology.Singapore medical journal · 2025Observational
- Health literacy and self-care among patients with chronic kidney disease in a primary care setting.Singapore medical journal · 2025Article
- Factors affecting disease progression in early-stage chronic kidney disease in a multi-ethnic, southeast Asian primary care population.Frontiers in medicine · 2025Article
- Exploring the association of calbindin -D28K in renal dialysis with oral health: a comprehensive review.Frontiers in oral health · 2025Review
- Economic Evaluation of Population-Level Chronic Kidney Disease Interventions in the UK National Health Service.Journal of health economics and outcomes research · 2025Article
- Analysis of chronic kidney disease epidemiology in Kazakhstan using nationwide data for 2014-2020 and forecasting future trends of prevalence and mortality for 2030.Renal failure · 2024Article
- Overview of global healthcare policies for patients with chronic kidney disease: an integrative literature review.Einstein (Sao Paulo, Brazil) · 2024Review
- Besieged on all sides: the future burden of high-temperature-related kidney disease.The Lancet regional health. Western Pacific · 2023Article
- Chronic Kidney Disease and Periodontitis Interplay-A Narrative Review.International journal of environmental research and public health · 2023Review
- ARIMA model for predicting chronic kidney disease and estimating its economic burden in China.BMC public health · 2022Article
- Red blood cell distribution width at admission predicts outcome in critically ill patients with kidney failure: a retrospective cohort study based on the MIMIC-IV database.Renal failure · 2022Article
- Nephrologist referrals of older patients with chronic kidney disease in Singapore: a cross-sectional study.BJGP open · 2022Article
- Unlocking Potential within Health Systems Using Privacy-Preserving Record Linkage: Exploring Chronic Kidney Disease Outcomes through Linked Data Modelling.Applied clinical informatics · 2022Article
- Validation of the kidney failure risk equation in predicting the risk of progression to kidney failure in a multi-ethnic Singapore chronic kidney disease cohort.Singapore medical journal · 2022Article
- A focus on CKD reporting and inappropriate prescribing among older patients discharged from geriatric and nephrology units throughout Italy: A nationwide multicenter retrospective cross-sectional study.Frontiers in pharmacology · 2022Article
- Prediction models used in the progression of chronic kidney disease: A scoping review.PloS one · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic Kidney Disease (CKD) is a major public health problem worldwide. There is limited literature on a model to project the number of people with CKD. This study projects the number of residents with CKD in Singapore by 2035 using a Markov model.
methodsA Markov model with nine mutually exclusive health states was developed according to the clinical course of CKD, based on a discrete time interval of 1 year. The model simulated the transition of cohorts across different health states from 2007 to 2035 using prevalence, incidence, mortality, disease transition, and disease detection rates.
resultsFrom 2007 to 2035, the number of residents with CKD is projected to increase from 316,521 to 887,870 and the prevalence from 12.2% to 24.3%. Patients with CKD stages 1-2 constituted the largest proportion. The proportion of undiagnosed cases will decline from 72.1% to 56.4%, resulting from faster progression to higher CKD stages and its eventual detection.
conclusionBy 2035, about one-quarter of the Singapore residents are expected to have CKD. National policies need to focus on primary disease prevention and early disease detection to avoid delayed treatment of CKD which eventually leads to end-stage renal disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.