Evidence map›Paper›PMID 30112192›Full record

ArticleFuture science OA2018

Use of Laser Speckle Contrast Analysis during pelvic surgery in a uterine transplantation model.

Srdjan Saso, Maria Tziraki, Neil T Clancy, Lipei Song, Timothy Bracewell-Milnes, Benjamin P Jones, Maya Al-Memar, Joseph Yazbek, Meen-Yau Thum, Ahmad Sayasneh and 4 more

Open access · goldAbstract read
In one paragraph

Article in Future science OA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Srdjan SasoDivision of Surgery & Cancer, Institute of Reproductive & Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0HS2 UK.
Maria TzirakiHamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London, London, SW7 2AZ3 UK.
Neil T ClancyHamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London, London, SW7 2AZ3 UK.
Lipei SongHamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London, London, SW7 2AZ3 UK.
Timothy Bracewell-MilnesDepartment of Obstetrics & Gynaecology, Chelsea & Westminster Hospital, Imperial College London, London, SW10 9NH4 UK.
Benjamin P JonesDivision of Surgery & Cancer, Institute of Reproductive & Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0HS2 UK.
Maya Al-MemarDivision of Surgery & Cancer, Institute of Reproductive & Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0HS2 UK.
Joseph YazbekWest London Gynaecological Cancer Centre, Queen Charlotte's Hospital, Hammersmith Hospital Campus, Imperial College London, Du Cane Road, London, W12 0NN6 UK.
Meen-Yau ThumThe Lister Hospital, Chelsea, London, SW1W 8RH7 UK.
Ahmad SayasnehGuy's & Thomas' Hospitals, London, SE1 7EH8 9 UK.
Tom BourneDivision of Surgery & Cancer, Institute of Reproductive & Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0HS2 UK.
James Richard SmithDivision of Surgery & Cancer, Institute of Reproductive & Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0HS2 UK.
Daniel S ElsonHamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London, London, SW7 2AZ3 UK.
Sadaf Ghaem-MaghamiDivision of Surgery & Cancer, Institute of Reproductive & Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0HS2 UK.
Imperial College London · GBHammersmith Hospital · GBLister Hospital · GBSt. Thomas Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimUterine transplantation (UTx) is proposed for treatment of uterine factor infertility. Our aim was to assess whether Endoscopic Laser Speckle Contrast Analysis (eLASCA) could evaluate pelvic blood flow at anastomotic sites required for sheep and rabbit UTx. RESULTS/METHODOLOGY: eLASCA detected blood flow in rabbit UTx #7 and #9. In sheep UTx #2, #3 and #5, the results allowed us to conclude that blood flow was present in the uterine graft following transplantation; and post-UTx, the animal had heart and respiratory rates, and oxygen saturation compatible with a normal hemodynamic status.

conclusionThese preliminary results establish the potential of Laser Speckle Contrast Analysis as noncontact and real-time tool for observation of spatially-resolved blood flow from which other parameters can be derived.

Indexed as

graft anastomosisoxygen saturationsurgical imagingtissue perfusionuterine transplantation

Identifiers

PMID30112192
PMCPMC6088268
OpenAlexW2886443325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.