Evidence map›Paper›PMID 30112185›Full record

ArticleFuture science OA2018

Luminal MCF-12A & myoepithelial-like Hs 578Bst cells form bilayered acini similar to human breast.

Anne Weber-Ouellette, Mélanie Busby, Isabelle Plante

Abstract read
In one paragraph

Article in Future science OA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anne Weber-OuelletteINRS - Institut Armand-Frappier, Laval, Quebec, H7V 1B7, Canada.
Mélanie BusbyINRS - Institut Armand-Frappier, Laval, Quebec, H7V 1B7, Canada.
Isabelle PlanteINRS - Institut Armand-Frappier, Laval, Quebec, H7V 1B7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epithelium's functional unit is the bilayered acinus, made of a layer of luminal cells, surrounded by a layer of basal cells mainly composed of myoepithelial cells.

aimThe aim of this study was to develop a reproducible and manipulable 3D co-culture model of the bilayered acinus MATERIALS &

methodsTwo different combinations of cell lines were co-cultured in Matrigel: SCp2 and SCg6 mice cells, or MCF-12A and Hs 578Bst human cell lines.

resultsConfocal microscopy analysis showed that only MCF-12A and Hs 578Bst cells could form some bilayered acini. This

Indexed as

3D co-culture modelaciniacinusbreastepitheliummammary gland

Identifiers

PMID30112185
PMCPMC6088263

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.