Evidence map›Paper›PMID 30112117›Full record

ArticleOncotarget2018

Stem-like and highly invasive prostate cancer cells expressing CD44v8-10 marker originate from CD44-negative cells.

Chiara Di Stefano, Paola Grazioli, Rosaria Anna Fontanella, Paola De Cesaris, Antonella D'Amore, Michele Regno, Donatella Starace, Fabrizio Padula, Micol Elena Fiori, Rita Canipari and 6 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cisplatin-Resistant CD44International journal of molecular sciences · 2022
    Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Chiara Di StefanoDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Paola GrazioliDepartment of Experimental Medicine, Sapienza University, Rome, Italy.
Rosaria Anna FontanellaDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Paola De CesarisDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Antonella D'AmoreDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Michele RegnoDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Donatella StaraceDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Fabrizio PadulaDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Micol Elena FioriDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
Rita CanipariDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Antonella StoppacciaroDivision of Pathology, Sant'Andrea University Hospital, Rome, Italy.
Margherita PesceDivision of Pathology, Sant'Andrea University Hospital, Rome, Italy.
Antonio FilippiniDepartment of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Antonio Francesco CampeseDepartment of Molecular Medicine, Sapienza University, Rome, Italy.
Elio Ziparo *Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Anna Riccioli *Department of Anatomy, Histology, Forensic Medicine and Orthopaedics, Section of Histology and Medical Embryology, Sapienza University, Rome, Italy.
Sapienza University of Rome · ITIstituto Superiore di Sanità · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In human prostate cancer (PCa), the neuroendocrine cells, expressing the prostate cancer stem cell (CSC) marker CD44, may be resistant to androgen ablation and promote tumor recurrence. During the study of heterogeneity of the highly aggressive neuroendocrine PCa cell lines PC3 and DU-145, we isolated and expanded

Indexed as

alternative splicingCD44invasivenessprostate stem cells

Identifiers

PMID30112117
PMCPMC6089404
OpenAlexW2884374979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.