Evidence map›Paper›PMID 30112105›Full record

ArticleOncotarget2018

NGAL promotes recruitment of tumor infiltrating leukocytes.

Francesco Pacifico, Luna Pisa, Stefano Mellone, Michele Cillo, Alessio Lepore, Antonio Leonardi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. NF-κB in Thyroid Cancer: An Update.International journal of molecular sciences · 2024
    Review
  2. Review
  3. NGAL as a Potential Target in Tumor Microenvironment.International journal of molecular sciences · 2021
    Review
  4. Observational
  5. Article
  6. Iron Metabolism in Cancer.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Francesco PacificoIstituto di Endocrinologia ed Oncologia Sperimentale, CNR, 80131 Naples, Italy.
Luna PisaDipartimento di Medicina Molecolare e Biotecnologie Mediche, "Federico II" University of Naples, 80131 Naples, Italy.
Stefano MelloneIstituto di Endocrinologia ed Oncologia Sperimentale, CNR, 80131 Naples, Italy.
Michele CilloDipartimento di Medicina Molecolare e Biotecnologie Mediche, "Federico II" University of Naples, 80131 Naples, Italy.
Alessio LeporeDipartimento di Medicina Molecolare e Biotecnologie Mediche, "Federico II" University of Naples, 80131 Naples, Italy.
Antonio LeonardiDipartimento di Medicina Molecolare e Biotecnologie Mediche, "Federico II" University of Naples, 80131 Naples, Italy.
University of Naples Federico II · ITInstitute for Experimental Endocrinology and Oncology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously shown that Neutrophil Gelatinase-Associated Lipocalin (NGAL) is strongly expressed in thyroid carcinomas, especially of anaplastic type, where it protects neoplastic cells from serum deprivation-induced apoptosis and enhances tumor invasivity by regulating MMP-9 activity. Here we demonstrate that NGAL-containing conditioned medium from human anaplastic thyroid carcinoma (ATC) cells is able to induce monocyte migration

Indexed as

cancerchemokineschemotaxisNF-κBNGAL

Identifiers

PMID30112105
PMCPMC6089389
OpenAlexW2884066530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.