Evidence map›Paper›PMID 30112008›Full record

ReviewJournal of tropical medicine2018

Amoebic Liver Abscess and Indigenous Alcoholic Beverages in the Tropics.

T Kumanan, V Sujanitha, S Balakumar, N Sreeharan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of tropical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Amebic liver abscess: An update.World journal of hepatology · 2024
    Review
  5. Intestinal Parasitic Infections in 2023.Gastroenterology research · 2023
    Review
  6. A Rare Cause of Fever of Unknown Origin: Amoebic Liver Abscess.Revista da Sociedade Brasileira de Medicina Tropical · 2023
    Article
  7. Tropical medicine and health · 2020
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

T KumananDepartment of Medicine, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.ORCID 0000-0001-5735-4713
V SujanithaDepartment of Medicine, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.ORCID 0000-0003-0330-7254
S BalakumarDepartment of Biochemistry, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.
N SreeharanDepartment of Medicine, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.
University of Jaffna · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amoebic liver abscess (ALA) seen commonly in the tropics is predominantly confined to adult males, especially those who consume locally brewed alcohol, although intestinal amoebiasis occurs in all age groups and in both genders. Whether the role of alcohol in the development of ALA is incidental and casual or whether alcohol is causally implicated has been debated. It has been argued that socioeconomic factors and poor sanitary conditions are the primary culprits that casually link alcohol to ALA. However, there has emerged an abundance of data that implicates alcohol in a more causal role in facilitating the extraintestinal invasion of the infective protozoan and the subsequent development of ALA. These factors include the role of alcohol in host immunity, parasitic proliferation, and invasion and in creating a conducive hepatic microenvironment. The contributory role of alcohol-induced increase in hepatic iron stores and lipid content is discussed. Late-stage liver disease with fibrosis seems to be protective for the development of ALA. Further research is necessary to elucidate the many possible mechanisms that predispose to hepatic amoebiasis, so that appropriate individual and population-based preventive measures can be implemented.

Identifiers

PMID30112008
PMCPMC6077556
OpenAlexW2816751475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.