Evidence map›Paper›PMID 30111990›Full record

ArticleTheScientificWorldJournal2018

10-Year Cardiovascular Disease Risk Estimation Based on Lipid Profile-Based and BMI-Based Framingham Risk Scores across Multiple Sociodemographic Characteristics: The Malaysian Cohort Project.

Boekhtiar Borhanuddin, Azmawati Mohd Nawi, Shamsul Azhar Shah, Noraidatulakma Abdullah, Syed Zulkifli Syed Zakaria, Mohd Arman Kamaruddin, Chandralekah S Velu, Norliza Ismail, Mohd Shaharom Abdullah, Salywana Ahmad Kamat and 3 more

Abstract read
In one paragraph

Article in TheScientificWorldJournal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. The association between obstructive sleep apnea risk and cardiovascular disease risk in midlife Thai women in the U.S.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. TheInternational journal of environmental research and public health · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Boekhtiar BorhanuddinUKM Medical Molecular Biology Institute (UMBI), Malaysia.ORCID 0000-0002-0755-1863
Azmawati Mohd NawiDepartment of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Malaysia.
Shamsul Azhar ShahUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Noraidatulakma AbdullahUKM Medical Molecular Biology Institute (UMBI), Malaysia.ORCID 0000-0002-7186-2455
Syed Zulkifli Syed ZakariaDepartment of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Cheras, 56000 Kuala Lumpur, Malaysia.
Mohd Arman KamaruddinUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Chandralekah S VeluUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Norliza IsmailUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Mohd Shaharom AbdullahUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Salywana Ahmad KamatUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Afifah AwangUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Mariatul Akma HamidUKM Medical Molecular Biology Institute (UMBI), Malaysia.
Rahman JamalUKM Medical Molecular Biology Institute (UMBI), Malaysia.ORCID 0000-0002-8354-8957

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) leads to high morbidity and mortality rate worldwide. Therefore, it is important to determine the risk of CVD across the sociodemographic factors to strategize preventive measures. The current study consisted of 53,122 adults between the ages of 35 and 65 years from The Malaysian Cohort project during recruitment phase from year 2006 to year 2012. Sociodemographic profile and physical activity level were assessed via self-reported questionnaire, whereas relevant CVD-related biomarkers and biophysical variables were measured to determine the Framingham Risk Score (FRS). The main outcome was the 10-year risk of CVD via FRS calculated based on lipid profile and body mass index (BMI) associated formulae. The BMI-based formula yielded a higher estimation of 10-year CVD risk than the lipid profile-based formula in the study for both males (median = 13.2% and 12.7%, respectively) and females (median = 4.3% and 4.2%, respectively). The subgroup with the highest risk for 10-year CVD events (based on both FRS formulae) was the Malay males who have lower education level and low physical activity level. Future strategies for the reduction of CVD risk should focus on screening via BMI-based FRS in this at-risk subpopulation to increase the cost-effectiveness of the prevention initiatives.

Indexed as

Socioeconomic FactorsAdultAgedBody Mass IndexCardiovascular DiseasesHumansLipidsMalaysiaMiddle AgedRisk AssessmentRisk FactorsLipids

Identifiers

PMID30111990
PMCPMC6077456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.