ArticleScientific reports2018
Nomogram for prediction of non-proliferative diabetic retinopathy in juvenile-onset type 1 diabetes: a cohort study in an Asian population.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 32 citations in OpenAlex.
- Construction of a dynamic prediction model for diabetic retinopathy risk in adults with adult-onset type 1 diabetes: a real-world longitudinal cohort study.Frontiers in clinical diabetes and healthcare · 2026Article
- A Nomogram for Predicting Vision-Threatening Diabetic Retinopathy Among Mild Diabetic Retinopathy Patients: A Case-Control and Prospective Study of Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Nomogram model predicts the risk of visual impairment in diabetic retinopathy: a retrospective study.BMC ophthalmology · 2022Article
- Predictive model for diabetic retinopathy under limited medical resources: A multicenter diagnostic study.Frontiers in endocrinology · 2022Article
- Clinical and Demographic Factors Associated With Diabetic Retinopathy Among Young Patients With Diabetes.JAMA network open · 2021Article
- Nasal Methicillin-ResistantMicroorganisms · 2021Article
- Higher HbA1c may reduce axial length elongation in myopic children: a comparison cohort study.Acta diabetologica · 2021Article
- Foveal avascular zone analysis by optical coherence tomography angiography in patients with type 1 and 2 diabetes and without clinical signs of diabetic retinopathy.International ophthalmology · 2021Article
- An online diabetic retinopathy screening tool for patients with type 2 diabetes.International journal of ophthalmology · 2021Article
- Nomogram Prediction Model for Diabetic Retinopathy Development in Type 2 Diabetes Mellitus Patients: A Retrospective Cohort Study.Journal of diabetes research · 2021Article
- Data Homogeneity Effect in Deep Learning-Based Prediction of Type 1 Diabetic Retinopathy.Journal of diabetes research · 2021Article
- Foveal avascular zone area analysis in juvenile-onset type 1 diabetes using optical coherence tomography angiography.Japanese journal of ophthalmology · 2020Article
- Glycosylated Hemoglobin A1c Improves the Performance of the Nomogram for Predicting the 5-Year Incidence of Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Risk factors for prevalent diabetic retinopathy and proliferative diabetic retinopathy in type 1 diabetes.Endocrine · 2019Observational
- Role of Systemic Factors in Improving the Prognosis of Diabetic Retinal Disease and Predicting Response to Diabetic Retinopathy Treatment.Ophthalmology scienceReview
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
Abstract
The need for screening for retinopathy in patients with type 1 diabetes mellitus (T1DM) has been emphasised, but diagnostic delays were reported when screening was done at fixed intervals. To establish an individualised risk-prediction model to assist screening non-proliferative diabetic retinopathy (NPDR) in T1DM, we performed a retrospective cohort study enrolling participants in the Chang Gung Juvenile Diabetes Eye Study. There were 413 patients with 12 381 records analysed from 2005 to 2015. A time-dependent Cox proportional hazard analysis was used to evaluate the risks of NPDR development and a nomogram with risk-stratification indicators was established based on the results. During 97 months of follow-up, 43 of 413 patients (10.4%) developed NPDR. Male sex (HR: 0.4, 95% CI: 0.19-0.85), age 5-14 years at onset of T1DM (6.38, 2.41-16.87), duration of diabetes (1.57, 1.41-1.75), and hemoglobin A1c level (1.56, 1.35-1.80) were independently associated with NPDR. Using the nomogram offers a quick method in the clinical setting to interpret the risk of NPDR development. Based on its weighting, each of the independent factors is allocated a score, and the total points indicate the probabilities of NPDR occurring within 6 months, 1 year, and 3 years.
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