Evidence map›Paper›PMID 30111884›Full record

ReviewNature communications2018

Resolution of chronic inflammatory disease: universal and tissue-specific concepts.

Georg Schett, Markus F Neurath

Open access · goldAbstract readReview
In one paragraph

Review in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 223 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
223citing papers in PubMed, 1 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

223 citing papers in PubMed, 1 synthesis or guideline pooled it, 416 citations in OpenAlex.

  1. Pooled it
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  9. Inflammation and Resolution in Obesity-Related Cardiovascular Disease.International journal of molecular sciences · 2026
    Review
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163 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Georg SchettDepartment of Internal Medicine 3, Friedrich-Alexander University Erlangen-Nürnberg and Universitatsklinikum Erlangen, 91054, Erlangen, Germany. georg.schett@uk-erlangen.de.
Markus F NeurathDepartment of Internal Medicine 1, Friedrich-Alexander University Erlangen-Nürnberg and Universitatsklinikum Erlangen, 91054, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation and its resolution is under-studied in medicine despite being essential for understanding the development of chronic inflammatory disease. In this review article, we discuss the resolution of inflammation in both a biological and translational context. We introduce the concept of impaired resolution leading to diseases like rheumatoid arthritis, Crohn's disease, and asthma, as well as the cellular and molecular components that contribute to resolution of joint, gut, and lung inflammation, respectively. Finally, we discuss potential intervention strategies for fostering the resolution process, and their implications for the therapy of inflammatory diseases.

Indexed as

AnimalsArthritis, RheumatoidAsthmaChronic DiseaseCrohn DiseaseCytokinesHumansInflammationInflammation MediatorsModels, ImmunologicalCytokinesInflammation Mediators

Identifiers

PMID30111884
PMCPMC6093916
OpenAlexW2885800801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.