ArticleBritish journal of cancer2018
Cigarette smoking and thyroid cancer risk: a cohort study.
Article in British journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 67 citations in OpenAlex.
- Sex-Specific Thyroid Dysfunction in Sulfur Mustard-Exposed Veterans With Different Injury Severity.Journal of applied toxicology : JAT · 2026Article
- CatBoost with physics-based metaheuristics for thyroid cancer recurrence prediction.BioData mining · 2025Article
- Environmental and lifestyle factors and risk of thyroid carcinoma: a cross-sectional study.Endocrine · 2025Article
- Pituitary-Thyroid Hormones and Related Indices in Euthyroid Type 2 Diabetes: Association With Thyroid Nodules.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- A Submucosal Moderately Poor Differentiated Laryngeal Squamous Cell Carcinoma Presenting as a Thyroid Mass: A Report of a New Case.Case reports in otolaryngology · 2025Article
- Causal effects of thyroid volume change on thyroid disease: a Mendelian randomization study.Gland surgery · 2024Article
- Underlying effect of SMAD4 gene polymorphism on risk prediction of papillary thyroid carcinoma in Chinese population.Heliyon · 2024Article
- Thyroid Cancer Prevalence, Risk Exposure, and Clinical Features Among Transgender Female Veterans.Journal of the Endocrine Society · 2024Article
- Thyroid Hormone Changes Correlate to Combined Breast Cancer with Primary Thyroid Cancer.Breast cancer (Dove Medical Press) · 2024Article
- Influence of metabolic syndrome and lifestyle factors on thyroid nodules in Chinese adult men: a cross-sectional study.European thyroid journal · 2023Article
- Cigarette smoking and thyroid cancer risk: A Mendelian randomization study.Cancer medicine · 2023Article
- Social engagement and allostatic load mediate between adverse childhood experiences and multimorbidity in mid to late adulthood: the Canadian Longitudinal Study on Aging.Psychological medicine · 2023Article
- Socioeconomic disparity in the association between fine particulate matter exposure and papillary thyroid cancer.Environmental health : a global access science source · 2023Article
- Variants in TPO rs2048722, PTCSC2 rs925489 and SEMA4G rs4919510 affect thyroid carcinoma susceptibility risk.BMC medical genomics · 2023Article
- Predictors of Thyroid Disorders among Men and Women: A Population-Based Study.Medical journal of the Islamic Republic of Iran · 2023Article
- Analysis of factors associated with abnormal thyroid function among medical staff in radiotherapy departments.Frontiers in public health · 2023Article
- [Latest Research Findings on Health Management Based on Saliva Testing].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022Review
- Association between Obesity Indexes and Thyroid Cancer Risk in Korean Women: Nested Case-Control Study.Cancers · 2022Article
- Variations inMolecular and clinical oncology · 2022Article
- Discrepancies of RET gene and risk of differentiated thyroid carcinoma.Cancer biomarkers : section A of Disease markers · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe evaluated the association between smoking status and thyroid cancer risk and whether this association is mediated by body mass index (BMI) and thyroid-stimulating hormone (TSH).
methodsWe performed a cohort study of 96,855 Korean adults who were followed annually or biennially for a median of 5.9 years.
resultsDuring 511,052.9 person-years of follow-up, 1,250 participants developed thyroid cancer. In men, we observed a dose-dependent inverse association between current smoking, pack-years, and thyroid cancer. After adjustment for confounders, adjusted hazard ratios (95% confidence intervals) for thyroid cancer comparing current and former smokers to never smokers were 0.58 (0.45-0.75) and 0.93 (0.73-1.18), respectively. After further adjustment for BMI and TSH as potential mediators, this association was slightly attenuated, but remained significant. For women, current smokers tended to have a lower risk of thyroid cancer, but this association did not reach statistical significance.
conclusionsIn this cohort study, current smoking was associated with a decreased risk of incident thyroid cancer in men but not in women and this association was observed even after adjusting for TSH and BMI levels as potential mediators. Further mechanistic studies are needed to elucidate the possible effect of smoking on the pathogenesis of thyroid cancer development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.