Evidence map›Paper›PMID 30111755›Full record

ReviewMedicines (Basel, Switzerland)2018

Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis.

Francesca Gado, Maria Digiacomo, Marco Macchia, Simone Bertini, Clementina Manera

Open access · goldAbstract readReview
In one paragraph

Review in Medicines (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Therapeutic use of medical Cannabis in neurological diseases: a clinical update.Journal of neural transmission (Vienna, Austria : 1996) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Francesca GadoDepartment of Pharmacy, University of Pisa, Pisa 56126, Italy. francesca.gado@for.unipi.it.
Maria DigiacomoDepartment of Pharmacy, University of Pisa, Pisa 56126, Italy. maria.digiacomo@unipi.it.ORCID 0000-0003-0653-6642
Marco MacchiaDepartment of Pharmacy, University of Pisa, Pisa 56126, Italy. marco.macchia@unipi.it.
Simone BertiniDepartment of Pharmacy, University of Pisa, Pisa 56126, Italy. simone.bertini@unipi.it.ORCID 0000-0001-8832-8075
Clementina ManeraDepartment of Pharmacy, University of Pisa, Pisa 56126, Italy. clementina.manera@unipi.it.ORCID 0000-0002-7379-5743
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent findings highlight the emerging role of the endocannabinoid system in the control of symptoms and disease progression in multiple sclerosis (MS). MS is a chronic, immune-mediated, demyelinating disorder of the central nervous system with no cure so far. It is widely reported in the literature that cannabinoids might be used to control MS symptoms and that they also might exert neuroprotective effects and slow down disease progression. This review aims to give an overview of the principal cannabinoids (synthetic and endogenous) used for the symptomatic amelioration of MS and their beneficial outcomes, providing new potentially possible perspectives for the treatment of this disease.

Indexed as

arachidonoylethanolamine (AEA) reuptake inhibitorscannabinoid receptorsendocannabinoid systemfatty acid amide hydrolase (FAAH) inhibitorsmonoacylglycerol lipase (MAGL) inhibitorsmultiple sclerosis

Identifiers

PMID30111755
PMCPMC6164967
OpenAlexW2885378568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.