Evidence map›Paper›PMID 30111705›Full record

ArticleViruses2018

Bacteriophage Sf6 Tailspike Protein for Detection of

Sonja Kunstmann, Tom Scheidt, Saskia Buchwald, Alexandra Helm, Laurence A Mulard, Angelika Fruth, Stefanie Barbirz

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  5. Development of a Magnetic Bead-Based Method for Specific Detection ofJournal of microbiology and biotechnology · 2023
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  6. NovelViruses · 2022
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  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. The Many Applications of Engineered Bacteriophages-An Overview.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sonja KunstmannPhysical Biochemistry, University of Potsdam, 14476 Potsdam, Germany. sonja.kunstmann@mpikg.mpg.de.
Tom ScheidtPhysical Biochemistry, University of Potsdam, 14476 Potsdam, Germany. ts599@cam.ac.uk.ORCID 0000-0002-0185-7730
Saskia BuchwaldPhysical Biochemistry, University of Potsdam, 14476 Potsdam, Germany. sb165329@uni-greifswald.de.
Alexandra HelmPhysical Biochemistry, University of Potsdam, 14476 Potsdam, Germany. ahelm@uni-potsdam.de.
Laurence A MulardInstitut Pasteur, Unité de Chimie des Biomolécules, 28 rue du Roux, 75015 Paris, France. laurence.mulard@pasteur.fr.
Angelika FruthNational Reference Centre for Salmonella and other Bacterial Enterics, Robert Koch Institute, 38855 Wernigerode, Germany. frutha@rki.de.
Stefanie BarbirzPhysical Biochemistry, University of Potsdam, 14476 Potsdam, Germany. barbirz@uni-potsdam.de.ORCID 0000-0001-6101-9862
University of Potsdam · DECentre National de la Recherche Scientifique · FRRobert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophage research is gaining more importance due to increasing antibiotic resistance. However, for treatment with bacteriophages, diagnostics have to be improved. Bacteriophages carry adhesion proteins, which bind to the bacterial cell surface, for example tailspike proteins (TSP) for specific recognition of bacterial O-antigen polysaccharide. TSP are highly stable proteins and thus might be suitable components for the integration into diagnostic tools. We used the TSP of bacteriophage Sf6 to establish two applications for detecting

Indexed as

Bacterial Typing TechniquesBiological AssayBacteriophagesCarbohydrate SequenceCloning, MolecularEnzyme-Linked Immunosorbent AssayEscherichia coliFluorescent DyesGene ExpressionGenetic VectorsGlycoside HydrolasesModels, MolecularO AntigensOxadiazolesPodoviridaeProtein Binding4-(N-(iodoacetoxy)ethyl-N-methyl)amino-7-nitrobenz-2-oxa-1,3-diazoleFluorescent DyesGlycoside HydrolasesO AntigensOxadiazolesRecombinant Proteinstailspike protein, bacteriophageViral Tail Proteinsbacteriophagefluorescence sensormicrotiter plate assayO-antigenserotypingShigella flexneritailspike proteins

Identifiers

PMID30111705
PMCPMC6116271
OpenAlexW2887453298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.