Evidence map›Paper›PMID 30111695›Full record

ArticleMolecules (Basel, Switzerland)2018

Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity.

Maureen Gumbo, Richard M Beteck, Tawanda Mandizvo, Ronnett Seldon, Digby F Warner, Heinrich C Hoppe, Michelle Isaacs, Dustin Laming, Christina C Tam, Luisa W Cheng and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. In vitro molecular assessment ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  2. Design, Synthesis and Antimicrobial Evaluation of NewInternational journal of molecular sciences · 2023
    Article
  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Maureen GumboFaculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. mgumbo1@gmail.com.ORCID 0000-0001-7018-4595
Richard M BeteckFaculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. richmbi1@yahoo.com.ORCID 0000-0002-6282-043X
Tawanda MandizvoFaculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. tmandizvo@gmail.com.
Ronnett SeldonDrug Discovery and Development Centre (H3-D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa. ronnett.seldon@uct.ac.za.
Digby F WarnerMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Rondebosch 7701, South Africa. Digby.Warner@uct.ac.za.ORCID 0000-0002-4146-0930
Heinrich C HoppeFaculty of Science, Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa. h.hoppe@ru.ac.za.
Michelle IsaacsCentre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. m.isaacs@ru.ac.za.
Dustin LamingCentre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. dustinlaming89@gmail.com.ORCID 0000-0003-2734-0999
Christina C TamFoodborne Toxin Detection and Prevention Research Unit, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA. christina.tam@ars.usda.gov.
Luisa W ChengFoodborne Toxin Detection and Prevention Research Unit, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA. luisa.cheng@ars.usda.gov.
Nicole LiuDepartment of Biological Sciences, University of the Pacific, Stockton, CA 95211, USA. n_liu@u.pacific.edu.
Kirkwood M LandDepartment of Biological Sciences, University of the Pacific, Stockton, CA 95211, USA. kland@PACIFIC.EDU.
Setshaba D KhanyeFaculty of Science, Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa. s.khanye@ru.ac.za.ORCID 0000-0003-0725-5738
Rhodes University · ZAAgricultural Research Service · USUniversity of Cape Town · ZAUniversity of the Pacific · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the increased interest in their application in the treatment of infectious diseases, boron-containing compounds have received a significant coverage in the literature. Herein, a small set of novel cinnamoly-oxaborole amides were synthesized and screened against nagana

Indexed as

AmidesAnimalsAnti-Infective AgentsBoron CompoundsCell SurvivalCinnamatesHeLa CellsHumansMycobacterium tuberculosisSmall Molecule LibrariesStructure-Activity RelationshipTrichomonas vaginalisTrypanocidal AgentsTrypanosoma brucei bruceiTrypanosomiasis, AfricanAmidesAnti-Infective AgentsBoron CompoundsCinnamatesSmall Molecule LibrariesTrypanocidal Agentsbenzoxaborolescinnamic acidsMycobacterium tuberculosistrichomoniasistrypanosomiasis

Identifiers

PMID30111695
PMCPMC6222898
OpenAlexW2887964279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.