ArticlemSphere2018
Tongue Microbiota and Oral Health Status in Community-Dwelling Elderly Adults.
Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- From culture-based to 16S sequencing approaches: oral microbiota changes in aging, frailty, and oral hypofunction - a systematic review.BMC oral health · 2026Pooled it
- Probiotics as an Adjunct Therapy for the Treatment of Halitosis, Dental Caries and Periodontitis.Probiotics and antimicrobial proteins · 2020Pooled it
- Trial
- Association between denture use, chewing ability, and all-cause mortality in middle-aged and older adults who exercised regularly in Korea.Scientific reports · 2021Trial
- Modulating Oral Microbiota to Prevent Dental Caries: A Microbial Ecology Approach.Dentistry journal · 2026Review
- Baseline Oral Microbiota Richness Is Associated with Training-Induced Improvements in Relative Handgrip Strength in Older Adults.Nutrients · 2026Article
- Effects of 4-week xylitol tablet intake on tongue microbiota composition in children: a single-arm pilot study.Microbiology spectrum · 2026Article
- Metagenomic analysis of tongue samples from healthy subjects identifies distinct microbiome orotypes.Journal of oral microbiology · 2026Article
- Shotgun metagenomic analysis of the tongue-coating microbiome reveals oral microbes and their functions in older adults with dementia.Journal of oral microbiology · 2026Article
- Characterization of subgingival plaque microbiota in patients with severe periodontitis using full-length 16S rRNA gene sequencing.Scientific reports · 2025Article
- Computerized tongue image analysis for non-invasive disease screening: a review.Chinese medicine · 2025Review
- The Role of Probiotics and Their Postbiotic Metabolites in Post-COVID-19 Syndrome.Molecules (Basel, Switzerland) · 2025Review
- The Effect of 6-Week Advanced Oral Care on Oral Microbiome and Mycobiome Composition in People With Dementia Living in Residential Aged Care.Clinical and experimental dental research · 2025Article
- The Oral-Gut Microbiota Axis Across the Lifespan: New Insights on a Forgotten Interaction.Nutrients · 2025Review
- Review
- Human oral microbiome and its influence on mental health and brain disorders.AIMS microbiology · 2025Review
- Article
- Association of oral fungal profiles with health status and bacterial composition in elderly adults receiving community support and home care service.Applied and environmental microbiology · 2024Article
- Oral microbial signatures associated with age and frailty in Canadian adults.Scientific reports · 2024Article
- Temporal stability of tongue microbiota in older patients - A pilot study.Journal of dental sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tongue microbiota are a dominant source of oral microbial populations that are ingested with saliva, and therefore careful attention is required for the maintenance of health of elderly adults, who are susceptible to aspiration of oral contents. This study aimed to investigate the variation in tongue microbiota among community-dwelling elderly adults. Following a dental examination, tongue coating was collected from a 15-mm-diameter circular area at the center of the tongue dorsum of 506 elderly adults aged 70 to 80 years inhabiting the town of Hisayama, Japan. The microbial composition and density were determined by a 16S rRNA gene sequencing approach using a next-generation sequencer and quantitative PCR analysis, respectively. Co-occurrence network analysis identified two cohabiting groups of predominant commensals, one of which was primarily composed of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.