Evidence map›Paper›PMID 30111619›Full record

ArticleG3 (Bethesda, Md.)2018

Early Diverging Insect-Pathogenic Fungi of the Order Entomophthorales Possess Diverse and Unique Subtilisin-Like Serine Proteases.

Jonathan A Arnesen, Joanna Małagocka, Andrii Gryganskyi, Igor V Grigoriev, Kerstin Voigt, Jason E Stajich, Henrik H De Fine Licht

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Transcriptional responses ofFrontiers in microbiology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Jonathan A ArnesenSection for Organismal Biology, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark.
Joanna MałagockaSection for Organismal Biology, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark.
Andrii GryganskyiDepartment of Biology, Duke University, Durham, North Carolina, USA.ORCID 0000-0002-6037-0092
Igor V GrigorievUS Department of Energy Joint Genome Institute, Walnut Creek, California, USA.
Kerstin VoigtJena Microbial Resource Collection (JMRC), Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Adolf-Reichwein-Str.23, 07745 Jena, Germany.
Jason E StajichDepartment of Plant Pathology and Microbiology, University of California, Riverside, California.ORCID 0000-0002-7591-0020
Henrik H De Fine LichtSection for Organismal Biology, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark hhdefinelicht@plen.ku.dk.ORCID 0000-0003-3326-5729
University of Copenhagen · DKDuke University · USJoint Genome Institute · USLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEUniversity of California, Riverside · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insect-pathogenic fungi use subtilisin-like serine proteases (SLSPs) to degrade chitin-associated proteins in the insect procuticle. Most insect-pathogenic fungi in the order Hypocreales (Ascomycota) are generalist species with a broad host-range, and most species possess a high number of SLSPs. The other major clade of insect-pathogenic fungi is part of the subphylum Entomophthoromycotina (Zoopagomycota, formerly Zygomycota) which consists of high host-specificity insect-pathogenic fungi that naturally only infect a single or very few host species. The extent to which insect-pathogenic fungi in the order Entomophthorales rely on SLSPs is unknown. Here we take advantage of recently available transcriptomic and genomic datasets from four genera within Entomophthoromycotina: the saprobic or opportunistic pathogens

Indexed as

Amino Acid MotifsAmino Acid SequenceAnimalsCatalytic DomainCluster AnalysisDatabases, Nucleic AcidEntomophthoralesInsectaPhylogenyPosition-Specific Scoring MatricesProtein DomainsSequence Analysis, DNASubtilisinsSubtilisinsearly-diverging fungiinsect-pathogenphylogenomicsproteasesSubtilase

Identifiers

PMID30111619
PMCPMC6169396
OpenAlexW2803031838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.