Evidence map›Paper›PMID 30111608›Full record

ArticleBlood2018

Loss-of-function zinc finger mutation in the

Margje Sinnema, Daisheng Song, Wei Guan, Johanna W H Janssen, Richard van Wijk, Bradleigh E Navalsky, Kai Peng, Albertine E Donker, Alexander P A Stegmann, Frank S Lee

Open access · bronzeAbstract readCase ReportsLetter
In one paragraph

Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  3. Review
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  8. Erythrocytosis: genes and pathways involved in disease development.Blood transfusion = Trasfusione del sangue · 2021
    Review
  9. Review
  10. Review
  11. Hypoxia Pathway Proteins are Master Regulators of Erythropoiesis.International journal of molecular sciences · 2020
    Review
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Margje SinnemaDepartment of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands.
Daisheng SongDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Wei GuanDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Johanna W H JanssenDepartment of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands.
Richard van WijkDepartment of Clinical Chemistry and Hematology, University Medical Center Utrecht, Utrecht, The Netherlands; and.ORCID 0000-0002-8236-8292
Bradleigh E NavalskyDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Kai PengDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Albertine E DonkerDepartment of Pediatric Hematology, Maxima Medical Center, Veldhoven, The Netherlands.
Alexander P A StegmannDepartment of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands.
Frank S LeeDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.ORCID 0000-0003-2511-1834
University of Pennsylvania · USMaastricht University · NLRadboud University Nijmegen · NLUnion Hospital · CNUniversity Medical Center Utrecht · NL

Funding

Control of Erythropoiesis by the Oxygen Sensor PHD2R01DK104796 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LEE, FRANK S · 2015 to 2019
$1.8M
High Altitude Adaptation: A Model for Chronic HypoxiaR33HL120751 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI LEE, FRANK S · 2016 to 2018
$1.5M
NHLBI NIH HHS R33 HL120751NIDDK NIH HHS R01 DK104796
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Loss of Function MutationAdolescentAmino Acid SequenceConsanguinityFemaleHumansHypoxia-Inducible Factor-Proline DioxygenasesPolycythemiaZinc FingersEGLN1 protein, humanHypoxia-Inducible Factor-Proline Dioxygenases

Identifiers

PMID30111608
PMCPMC6161772
OpenAlexW2887057062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.