Evidence map›Paper›PMID 30111569›Full record

ArticleJournal of virology2018

Transcriptome Analysis of Infected and Bystander Type 2 Alveolar Epithelial Cells during Influenza A Virus Infection Reveals

Aidan S Hancock, Christopher J Stairiker, Alina C Boesteanu, Elisa Monzón-Casanova, Sebastian Lukasiak, Yvonne M Mueller, Andrew P Stubbs, Adolfo García-Sastre, Martin Turner, Peter D Katsikis

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Review
  3. Scar wars: the viral menace.American journal of physiology. Lung cellular and molecular physiology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Contribution ofeLife · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Aidan S Hancock *Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Christopher J Stairiker *Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Alina C BoesteanuDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Elisa Monzón-CasanovaLaboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge, United Kingdom.
Sebastian LukasiakLaboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge, United Kingdom.
Yvonne M MuellerDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Andrew P StubbsDepartment of Bioinformatics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Adolfo García-SastreDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Martin TurnerLaboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge, United Kingdom martin.turner@babraham.ac.uk p.katsikis@erasmusmc.nl.
Peter D KatsikisDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA martin.turner@babraham.ac.uk p.katsikis@erasmusmc.nl.ORCID https://orcid.org/0000-0001-7690-5218
Erasmus MC · NLBabraham Institute · GBDrexel University · USIcahn School of Medicine at Mount Sinai · US

Funding

Virus CoreU19AI106754 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALBRECHT, RANDY A. · 2013 to 2017
$26.0M
Medical Research Council G1001068NIAID NIH HHS HHSN272201400008CNIAID NIH HHS U19 AI106754
6 · The paper itself

Abstract

Influenza virus outbreaks remain a serious threat to public health. A greater understanding of how cells targeted by the virus respond to the infection can provide insight into the pathogenesis of disease. Here we examined the transcriptional profile of

Indexed as

A549 CellsAlveolar Epithelial CellsAnimalsCell LineDogsFemaleGene Expression ProfilingHumansInfluenza A Virus, H1N1 SubtypeInterferon LambdaInterferonsInterferon Type IMadin Darby Canine Kidney CellsMiceMice, Inbred C57BLOrthomyxoviridae InfectionsInterferon LambdaInterferonsInterferon Type Ialveolar epithelial cellsinfluenzatranscriptomeWnt signaling

Identifiers

PMID30111569
PMCPMC6189488
OpenAlexW2885028674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.