ArticleThe international journal of behavioral nutrition and physical activity2018
The multivariate physical activity signature associated with metabolic health in children.
Article in The international journal of behavioral nutrition and physical activity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02132494 (Active Smarter Kids), which is not on this map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Active Smarter Kids: A Cluster-randomized Controlled Trial Investigating the Effect of Daily Physical Activity on Children's Academic Performance and on Risk Factors for Lifestyle-related Non-communicable Diseases
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association between 24-hour movement behaviors and adiposity in children and adolescents: A compositional data meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- A Standardised Core Outcome Set for Measurement and Reporting Sedentary Behaviour Interventional Research: The CROSBI Consensus Study.International journal of environmental research and public health · 2022Pooled it
- Current Evidence of Measurement Properties of Physical Activity Questionnaires for Older Adults: An Updated Systematic Review.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Investigating between-group effects of a physical activity intervention across the physical activity intensity spectrum using multivariate pattern analysis.BMC public health · 2025Trial
- Linking 23 physical activity intensity levels to health-related quality of life in 10-year-old children.BMC research notes · 2025Trial
- Efficacy of education outside the classroom to increase adolescent physical activity.Scientific reports · 2024Trial
- Multicollinear physical activity accelerometry data and associations to cardiometabolic health: challenges, pitfalls, and potential solutions.The international journal of behavioral nutrition and physical activity · 2019Trial
- Article
- Physical activity partially mediating the social gradient in adolescent mental health.Frontiers in public health · 2025Article
- Accelerometer-Measured Physical Activity, Fitness and Indicators of Cardiometabolic Risk among Rural Adolescents: A Cross-Sectional Study at 15-Year Follow-up of the MINIMat Cohort.Journal of epidemiology and global health · 2024Article
- Charting the cascade of physical activities: implications for reducing sitting time and obesity in children.Journal of activity, sedentary and sleep behaviors · 2024Article
- Multivariate pattern analysis: a method and software to reveal, quantify, and visualize predictive association patterns in multicollinear data.BMC bioinformatics · 2024Article
- Association between biomarkers of redox status and cytokines with different patterns of habitual physical activity in eutrophic and overweight/obese preschoolers: multivariate analysis of a cross-sectional study.BMC public health · 2023Article
- The association between reallocations of time and health using compositional data analysis: a systematic scoping review with an interactive data exploration interface.The international journal of behavioral nutrition and physical activity · 2023Article
- Optimal domain-specific physical activity and sedentary behaviors for blood lipids among Japanese children: a compositional data analysis.Journal of activity, sedentary and sleep behaviors · 2023Article
- Tortoise or Hare? The Associations between Physical Activity Volume and Intensity Distribution and the Risk of All-Cause Mortality: A Large Prospective Analysis of the UK Biobank.International journal of environmental research and public health · 2023Article
- Factors associated with physical activity participation among children: a systematic review protocol.Systematic reviews · 2023Article
- How Do Health, Biological, Behavioral, and Cognitive Variables Interact over Time in Children of Both Sexes? A Complex Systems Approach.International journal of environmental research and public health · 2023Article
- The Goldilocks Day for healthy adiposity measures among children and adolescents.Frontiers in public health · 2023Article
- The multivariate physical activity signatures associated with body mass index and waist-to-height ratio in 3-5-year-old Norwegian children.Preventive medicine reports · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundPhysical activity is a cornerstone for promoting good metabolic health in children, but it is heavily debated which intensities (including sedentary time) are most influential. A fundamental limitation to current evidence for this relationship is the reliance on analytic approaches that cannot handle collinear variables. The aim of the present study was to determine the physical activity signature related to metabolic health in children, by investigating the association pattern for the whole spectrum of physical activity intensities using multivariate pattern analysis.
methodsWe used a sample of 841 children (age 10.2 ± 0.3 years; BMI 18.0 ± 3.0; 50% boys) from the Active Smarter Kids study, who provided valid data on accelerometry (ActiGraph GT3X+) and several indices of metabolic health (aerobic fitness, abdominal fatness, insulin sensitivity, lipid metabolism, blood pressure) that were used to create a composite metabolic health score. We created 16 physical activity variables covering the whole intensity spectrum (from 0-100 to ≥ 8000 counts per minute) and used multivariate pattern analysis to analyze the data.
resultsPhysical activity intensities in the vigorous range (5000-7000 counts per minute) were most strongly associated with metabolic health. Moderate intensity physical activity was weakly related to health, and sedentary time and light physical activity were not related to health.
conclusionsThis study is the first to determine the multivariate physical activity signature related to metabolic health in children across the whole intensity spectrum. This novel approach shows that vigorous physical activity is strongest related to metabolic health. We recommend future studies adapt a multivariate analytic approach to further develop the field of physical activity epidemiology.
trial registrationThe study was registered in Clinicaltrials.gov (www.clinicaltrials.gov) 7th of April 2014 with identification number NCT02132494 .
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.