Evidence map›Paper›PMID 30111355›Full record

ArticleActa neuropathologica communications2018

CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response.

Stefanie Stallard, Masha G Savelieff, Kyle Wierzbicki, Brendan Mullan, Zachary Miklja, Amy Bruzek, Taylor Garcia, Ruby Siada, Bailey Anderson, Benjamin H Singer and 10 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Stefanie StallardDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Masha G SavelieffSciGency Science Communications, Ann Arbor, MI, 48104, USA.
Kyle WierzbickiDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Brendan MullanDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Zachary MikljaDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Amy BruzekDepartment of Neurosurgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Taylor GarciaDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Ruby SiadaDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Bailey AndersonDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Benjamin H SingerDepartment of Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Rintaro HashizumeDepartment of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Angel M CarcabosoDepartment of Oncology, Hospital Sant Joan de Déu, 08950, Barcelona, Spain.
Kaitlin Q McMurrayDepartment of Neurosurgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Jason HethDepartment of Neurosurgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Karin MuraszkoDepartment of Neurosurgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Patricia L RobertsonDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Rajen ModyDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA.
Sriram VennetiDepartment of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Hugh GartonDepartment of Neurosurgery, Michigan Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Carl KoschmannDepartment of Pediatrics, Michigan Medicine, University of Michigan Medical School, 3520D MSRB I, 1150 W Medical Center Drive, Ann Arbor, MI, 48109, USA. ckoschma@med.umich.edu.ORCID 0000-0002-0825-7615

Funding

Targeting histone demethylase activity for the treatment of pediatric brainstem gliomaR01NS093079 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HASHIZUME, RINTARO · 2015 to 2019
$1.5M
β-Amyloid Potentiates Neuroinflammation and Cognitive Decline After Sepsis SurvivalK08NS101054 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SINGER, BENJAMIN HERSCHEL · 2017 to 2021
$1.0M
Targeting ATRX-Deficient Pediatric GBMK08NS099427 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOSCHMANN, CARL J · 2017 to 2021
$811k
NINDS NIH HHS K08 NS099427NINDS NIH HHS K08 NS101054NINDS NIH HHS R01 NS093079
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentBrain NeoplasmsCell ProliferationChildCirculating Tumor DNADNA Copy Number VariationsFemaleGliomaHistonesHumansIn Vitro TechniquesLysineMagnetic Resonance ImagingMaleMethionineMutationCirculating Tumor DNAH3-3A protein, humanHistonesLysineMethionine

Identifiers

PMID30111355
PMCPMC6094898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.