Evidence map›Paper›PMID 30111305›Full record

ArticleBMC infectious diseases2018

Comparison of crowd-sourced, electronic health records based, and traditional health-care based influenza-tracking systems at multiple spatial resolutions in the United States of America.

Kristin Baltrusaitis, John S Brownstein, Samuel V Scarpino, Eric Bakota, Adam W Crawley, Giuseppe Conidi, Julia Gunn, Josh Gray, Anna Zink, Mauricio Santillana

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04663776 (Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04663776 completednot on this mapstarted 2020, after this paper: background citation

Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform

TypeobservationalSponsorBoston Children's HospitalRan2020 to 2021Enrolled16,000ConditionsCovid19, Influenza, Respiratory Tract Infections, Acute Respiratory Tract Infection
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
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  13. Crowdsourced disease surveillance success story: The FluWatchers program.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
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  20. Socioeconomic bias in influenza surveillance.PLoS computational biology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kristin BaltrusaitisComputational Health Informatics Program, Boston Children's Hospital, Boston, MA, 02115, USA. kbalt2@bu.edu.ORCID 0000-0003-2090-9513
John S BrownsteinComputational Health Informatics Program, Boston Children's Hospital, Boston, MA, 02115, USA.
Samuel V ScarpinoDepartment of Mathematics and Statistics, University of Vermont, Vermont, USA.
Eric BakotaCity of Houston Health Department, Houston, TX, 77054, USA.
Adam W CrawleySkoll Global Threats Fund, San Francisco, CA, USA.
Giuseppe ConidiBoston Public Health Commission, Boston, MA, USA.
Julia GunnBoston Public Health Commission, Boston, MA, USA.
Josh GrayathenaResearch at athenahealth, Watertown, MA, USA.
Anna ZinkathenaResearch at athenahealth, Watertown, MA, USA.
Mauricio SantillanaComputational Health Informatics Program, Boston Children's Hospital, Boston, MA, 02115, USA. msantill@g.harvard.edu.

Funding

Interdisciplinary Training for BiostatisticiansT32GM074905 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WHITE, LAURA FORSBERG · 2005 to 2019
$3.0M
Development of an Open-Source and Data-Driven Modeling Platform to Monitor and Forecast Disease ActivityR01GM130668 · NIGMS · NORTHEASTERN UNIVERSITY · PI SANTILLANA, MAURICIO · 2018 to 2022
$1.9M
NIGMS NIH HHS R01 GM130668NIGMS NIH HHS T32 GM074905NIH HHS T32GM074905
6 · The paper itself

Abstract

backgroundInfluenza causes an estimated 3000 to 50,000 deaths per year in the United States of America (US). Timely and representative data can help local, state, and national public health officials monitor and respond to outbreaks of seasonal influenza. Data from cloud-based electronic health records (EHR) and crowd-sourced influenza surveillance systems have the potential to provide complementary, near real-time estimates of influenza activity. The objectives of this paper are to compare two novel influenza-tracking systems with three traditional healthcare-based influenza surveillance systems at four spatial resolutions: national, regional, state, and city, and to determine the minimum number of participants in these systems required to produce influenza activity estimates that resemble the historical trends recorded by traditional surveillance systems.

methodsWe compared influenza activity estimates from five influenza surveillance systems: 1) patient visits for influenza-like illness (ILI) from the US Outpatient ILI Surveillance Network (ILINet), 2) virologic data from World Health Organization (WHO) Collaborating and National Respiratory and Enteric Virus Surveillance System (NREVSS) Laboratories, 3) Emergency Department (ED) syndromic surveillance from Boston, Massachusetts, 4) patient visits for ILI from EHR, and 5) reports of ILI from the crowd-sourced system, Flu Near You (FNY), by calculating correlations between these systems across four influenza seasons, 2012-16, at four different spatial resolutions in the US. For the crowd-sourced system, we also used a bootstrapping statistical approach to estimate the minimum number of reports necessary to produce a meaningful signal at a given spatial resolution.

resultsIn general, as the spatial resolution increased, correlation values between all influenza surveillance systems decreased. Influenza-like Illness rates in geographic areas with more than 250 crowd-sourced participants or with more than 20,000 visit counts for EHR tracked government-lead estimates of influenza activity.

conclusionsWith a sufficient number of reports, data from novel influenza surveillance systems can complement traditional healthcare-based systems at multiple spatial resolutions.

Indexed as

CrowdsourcingDisease OutbreaksElectronic Health RecordsHumansInfluenza, HumanMassachusettsPopulation SurveillanceUnited StatesCommunity-based participatory researchCrowd-sourcingDigital disease detectionInfluenzaPublic health informaticsPublic health surveillance

Identifiers

PMID30111305
PMCPMC6094455

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.