Evidence map›Paper›PMID 30111303›Full record

ArticleBMC pregnancy and childbirth2018

Comparison of logistic regression with machine learning methods for the prediction of fetal growth abnormalities: a retrospective cohort study.

Stefan Kuhle, Bryan Maguire, Hongqun Zhang, David Hamilton, Alexander C Allen, K S Joseph, Victoria M Allen

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 176 citations in OpenAlex.

  1. Pooled it
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  10. Machine learning versus traditional formulas for fetal weight estimation: An international multicenter study evaluating prediction accuracy across birth weight percentiles.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  12. Antepartum prediction of shoulder dystocia using machine learning.Archives of gynecology and obstetrics · 2025
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  16. Predicting Fetal Growth with Curve Fitting and Machine Learning.Bioengineering (Basel, Switzerland) · 2025
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stefan KuhlePerinatal Epidemiology Research Unit, Departments of Obstetrics & Gynaecology and Pediatrics, Dalhousie University, Halifax, NS, Canada. stefan.kuhle@dal.ca.ORCID http://orcid.org/0000-0001-9417-3727
Bryan MaguirePerinatal Epidemiology Research Unit, Departments of Obstetrics & Gynaecology and Pediatrics, Dalhousie University, Halifax, NS, Canada.
Hongqun ZhangDepartment of Mathematics & Statistics, Dalhousie University, Halifax, NS, Canada.
David HamiltonDepartment of Mathematics & Statistics, Dalhousie University, Halifax, NS, Canada.
Alexander C AllenPerinatal Epidemiology Research Unit, Departments of Obstetrics & Gynaecology and Pediatrics, Dalhousie University, Halifax, NS, Canada.
K S JosephDepartment of Obstetrics & Gynaecology and School of Population & Public Health, University of British Columbia, Vancouver, BC, Canada.
Victoria M AllenDepartment of Obstetrics & Gynaecology, Dalhousie University, Halifax, NS, Canada.
Dalhousie University · CAUniversity of British Columbia · CA

Funding

Canadian Institutes of Health Research 134531Canadian Institutes of Health Research PSO-RPP-2005-2-1031IWK Health Centre 09020
6 · The paper itself

Abstract

backgroundWhile there is increasing interest in identifying pregnancies at risk for adverse outcome, existing prediction models have not adequately assessed population-based risks, and have been based on conventional regression methods. The objective of the current study was to identify predictors of fetal growth abnormalities using logistic regression and machine learning methods, and compare diagnostic properties in a population-based sample of infants.

methodsData for 30,705 singleton infants born between 2009 and 2014 to mothers resident in Nova Scotia, Canada was obtained from the Nova Scotia Atlee Perinatal Database. Primary outcomes were small (SGA) and large for gestational age (LGA). Maternal characteristics pre-pregnancy and at 26 weeks were studied as predictors. Logistic regression and select machine learning methods were used to build the models, stratified by parity. Area under the curve was used to compare the models; relative importance of predictors was compared qualitatively.

results7.9% and 13.5% of infants were SGA and LGA, respectively; 48.6% of births were to primiparous women and 51.4% were to multiparous women. Prediction of SGA and LGA was poor to fair (area under the curve 60-75%) and improved with increasing parity and pregnancy information. Smoking, previous low birthweight infant, and gestational weight gain were important predictors for SGA; pre-pregnancy body mass index, gestational weight gain, and previous macrosomic infant were the strongest predictors for LGA.

conclusionsThe machine learning methods used in this study did not offer any advantage over logistic regression in the prediction of fetal growth abnormalities. Prediction accuracy for SGA and LGA based on maternal information is poor for primiparous women and fair for multiparous women.

Indexed as

Gestational Weight GainLogistic ModelsMachine LearningAdultBody Mass IndexCohort StudiesFemaleFetal DevelopmentFetal MacrosomiaHumansInfant, NewbornInfant, Small for Gestational AgeNeural Networks, ComputerNova ScotiaPregnancyPregnancy Trimester, SecondBirth weightFetal growth restrictionFetal macrosomiaInfantPredictionPregnancy

Identifiers

PMID30111303
PMCPMC6094446
OpenAlexW2885070421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.