Evidence map›Paper›PMID 30110930›Full record

ReviewBrain sciences2018

Transcranial Direct Current Stimulation (tDCS) for Depression during Pregnancy: Scientific Evidence and What Is Being Said in the Media-A Systematic Review.

Anna Katharina Kurzeck, Beatrice Kirsch, Elif Weidinger, Frank Padberg, Ulrich Palm

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Brain sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05389345 nawithdrawnnot on this mapstarted 2021, after this paper: background citation

Effects of Adding Transcranial Direct Current Stimulation to Executive Function Training for Schizophrenia-spectrum Disorders - a Randomized Control Trial

TypeinterventionalSponsorUniversity of TorontoRan2021 to 2023Enrolled0ConditionsSchizophrenia, Schizophrenia Spectrum Disorder, Schizophrenia and Related DisordersArmsTranscranial direct current stimulation, Executive function training
NCT06015425 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Real-world Data Collection and Real-world Evidence Clinical Demonstration Study of tDCS for the Treatment of Depression in Perinatal Women

TypeinterventionalSponsorSeoul National University HospitalRan2023 to 2025Enrolled125ConditionsDepression, PregnancyArmsMINDD STIM+
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna Katharina KurzeckDepartment of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilian University, 80336 Munich, Germany. annakatharina.kurzeck@t-online.de.
Beatrice KirschDepartment of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilian University, 80336 Munich, Germany. beatrice.kirsch@med.uni-muenchen.de.
Elif WeidingerDepartment of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilian University, 80336 Munich, Germany. elif.weidinger@med.uni-muenchen.de.
Frank PadbergDepartment of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilian University, 80336 Munich, Germany. frank.padberg@med.uni-muenchen.de.
Ulrich PalmDepartment of Psychiatry and Psychotherapy, Klinikum der Universität München, Ludwig-Maximilian University, 80336 Munich, Germany. ulrich.palm@med.uni-muenchen.de.ORCID 0000-0002-5446-8237

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Major depression is the most frequent morbidity in pregnancy. The first-line therapies, psychopharmacologic treatment and psychotherapy, are either insufficient or may cause severe or teratogenic adverse events. As a result of its local limitation to the patient's brain, transcranial direct current stimulation (tDCS) could potentially be an ideal treatment for pregnant women with depression. A literature search was conducted in medical databases, globally published newspapers, search engines, and clinical trial registers to collect all articles on tDCS for the treatment of depression during pregnancy. The aim of this review was to investigate the scientific evidence of tDCS use for depression during pregnancy and to compare these results with the textual and emotional perception in the media as interventions during pregnancy are under particular surveillance. We detected 13 medical articles dealing with tDCS for depression in pregnancy. Overall, the scientific evidence as well as articles in the media for tDCS in pregnancy are sparse, but promising. Further studies are required in this specifically vulnerable population of pregnant women to generate evidence. It is likely that public interest will increase when the results of a pilot study in Canada are published.

Indexed as

antenataldepressionnon-invasive brain stimulationpregnancypregnanttDCStranscranial direct current stimulation

Identifiers

PMID30110930
PMCPMC6119899

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.