ReviewMaterials (Basel, Switzerland)2018
Osteogenic Potential of Graphene in Bone Tissue Engineering Scaffolds.
Review in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Recent Advances in Graphene Oxide-Based on Organoid Culture as Disease Model and Cell Behavior - A Systematic Literature Review.International journal of nanomedicine · 2024Pooled it
- Graphene Oxide-Hydroxyapatite Nanocomposite Coatings and Extracellular Matrix Protein Interactions for Enhanced Osseointegration in Dental Implants.Journal of cellular and molecular medicine · 2026Article
- Leveraging Nanoscience and Strategic Delivery for the Expedition of Osteoporosis.AAPS PharmSciTech · 2025Review
- Osteoinductive potential of graphene and graphene oxide for bone tissue engineering: a comparative study.Journal of orthopaedic surgery and research · 2024Article
- Graphene and its hybrid nanocomposite: A Metamorphoses elevation in the field of tissue engineering.Heliyon · 2024Review
- Analyzing the Surface Topography of Hafnium Nitride Coating on Titanium Screws: An In Vitro Analysis.Cureus · 2024Article
- Graphene: A Multifaceted Carbon-Based Material for Bone Tissue Engineering Applications.ACS omega · 2024Review
- Drug Loaded 3D-Printed Poly(ε-Caprolactone) Scaffolds for Local Antibacterial or Anti-Inflammatory Treatment in Bone Regeneration.Polymers · 2023Article
- Novel Application of 3D Scaffolds of Poly(E-Caprolactone)/Graphene as Osteoinductive Properties in Bone Defect.European journal of dentistry · 2023Article
- Article
- Graphene-Related Nanomaterials for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2023Review
- PCL/Graphene Scaffolds for the Osteogenesis Process.Bioengineering (Basel, Switzerland) · 2023Article
- Double-Reinforced Fish Gelatin Composite Scaffolds for Osteochondral Substitutes.Materials (Basel, Switzerland) · 2023Article
- Repairing rat calvarial defects by adipose mesenchymal stem cells and novel freeze-dried three-dimensional nanofibrous scaffolds.BioImpacts : BI · 2023Article
- Advancement inJournal of environmental health science & engineering · 2022Review
- Graphene Incorporated Electrospun Nanofiber for Electrochemical Sensing and Biomedical Applications: A Critical Review.Sensors (Basel, Switzerland) · 2022Review
- Bone Healing in Rat Segmental Femur Defects with Graphene-PCL-Coated Borate-Based Bioactive Glass Scaffolds.Polymers · 2022Article
- 3D-Printing Graphene Scaffolds for Bone Tissue Engineering.Pharmaceutics · 2022Review
- Carbon nanostructures: a comprehensive review of potential applications and toxic effects.3 Biotech · 2022Review
- Poly(Gels (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scaffolds are physical substrates for cell attachments, proliferation, and differentiation, ultimately leading to tissue regeneration. Current literature validates tissue engineering as an emerging tool for bone regeneration. Three-dimensionally printed natural and synthetic biomaterials have been traditionally used for tissue engineering. In recent times, graphene and its derivatives are potentially employed for constructing bone tissue engineering scaffolds because of their osteogenic and regenerative properties. Graphene is a synthetic atomic layer of graphite with SP2 bonded carbon atoms that are arranged in a honeycomb lattice structure. Graphene can be combined with natural and synthetic biomaterials to enhance the osteogenic potential and mechanical strength of tissue engineering scaffolds. The objective of this review is to focus on the most recent studies that attempted to explore the salient features of graphene and its derivatives. Perhaps, a thorough understanding of the material science can potentiate researchers to use this novel substitute to enhance the osteogenic and biological properties of scaffold materials that are routinely used for bone tissue engineering.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.