ArticlePloS one2018
Multiple birth rates of Korea and fetal/neonatal/infant mortality in multiple gestation.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- A machine learning approach to identify key socio-economic and demographic factors associated with neonatal mortality in Ethiopia.BMC public health · 2026Article
- Remdesivir Use During Pregnancy: Findings From the Prospective COVID-19 International Drug Pregnancy Registry and Narrative Literature Review.Journal of pregnancy · 2026Review
- Infant mortality rate and time to death determinants in East Africa: A Bayesian spatial frailty analysis of DHS data (2015-2022).PloS one · 2026Article
- Machine learning for preventing stillbirths: is it possible to transform data into life-saving insights?BMC pregnancy and childbirth · 2025Article
- Trends and characteristics of triplet births in a tertiary maternity hospital in China: A retrospective study over two decades.European journal of obstetrics & gynecology and reproductive biology: X · 2025Article
- Maternal, Perinatal and Neonatal Outcomes of Triplet Pregnancies According to Chorionicity: Our 15-Year Experience in a Tertiary-Level Center.Journal of clinical medicine · 2024Article
- The Contribution of Multiple Pregnancies in Stillbirths in Greece: A Time-Trend Analysis.Cureus · 2024Article
- Factors associated with preventable infant mortality in 2020: a Brazilian population-based study.Revista brasileira de enfermagem · 2024Article
- Mortality of neonates born to mothers of extreme reproductive age in Ethiopia; multilevel mixed effect analysis of Ethiopian demographic and health survey data of 2016.Frontiers in pediatrics · 2024Article
- Modulation of Melatonin Receptors Regulates Reproductive Physiology: The Impact of Agomelatine on the Estrus Cycle, Gestation, Offspring, and Uterine Contractions in Rats.Physiological research · 2023Article
- Prediction of Pregnancy-Associated Hypertension Using a Scoring System: A Multicenter Cohort Study.Life (Basel, Switzerland) · 2023Article
- Serum hsCRP in early pregnancy and preterm delivery in twin gestations: a prospective cohort study.BMC pregnancy and childbirth · 2023Article
- Article
- Article
- Effects of antenatal corticosteroids on neonatal outcomes in twin and singleton pregnancies: a Korean national cohort study.BMJ paediatrics open · 2023Article
- Maternal, Perinatal and Neonatal Outcomes of Triplet Pregnancies According to Chorionicity: A Systematic Review of the Literature and Meta-Analysis.Journal of clinical medicine · 2022Article
- Association between pregravid liver enzyme levels and gestational diabetes in twin pregnancies: a secondary analysis of national cohort study.Scientific reports · 2021Article
- The Combined Effects of Fine Particulate Matter and Temperature on Preterm Birth in Seoul, 2010-2016.International journal of environmental research and public health · 2021Article
- Effect of Cervical Cerclage on the Risk of Recurrent Preterm Birth after a Twin Spontaneous Preterm Birth.Journal of Korean medical science · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study was conducted to analyze recent trends of multiple birth rates (MBR) and fetal/neonatal/infant mortalities according to the number of gestations in Korea.
methodsData from 2009 to 2015 of live births, infant deaths and stillbirths were obtained from the Korean Vital Statistics. Neonatal mortality rate (NMR), infant mortality rate (IMR), and fetal mortality rate (FMR) in singleton, twin and triplet pregnancies were analyzed according to gestational period (GP; ≤ 23, 24-27, 28-31, and 32-36 weeks).
resultsFrom 2009 to 2015, twin and triplet birth rates increased 34.5% and 154.3%, respectively. In twin births, NMR and FMR have been decreased significantly (from 10.92 to 8.62, p = 0.034 and from 41.00 to 30.55, p< 0.001, respectively), but IMR did not show significant decrease. There was no significant change of NMR, IMR, and FMR, in triplet births. Overall, in singleton, twin, and triplet births, NMR was 1.26 ± 0.09, 10.6 ± 1.12, and 34.32 ± 11.72, respectively, and IMR was 2.38 ± 0.26, 14.52 ± 1.38, and 41.13 ± 12.2, respectively. FMRs were 12 ± 1.73, 35.99 ± 3.55, and 88.85 ± 16.55, respectively, in singleton, twin, and triplet pregnancies. In spite of decreasing trends in overall mortalities, the odds ratios of NMRs and IMRs in 2015 were approximately 9-fold and 6-fold higher, respectively, in twin births, and approximately 37-fold and 20-fold higher, respectively, in triplet births, than those in singleton births. There were no significant differences in odds ratios of NMRs and IMRs at GP 32-36 among single, twin, and triplet births, although the odds ratios of FMR at GP 32-36 in triplet gestation was significantly higher than those in singleton and twin gestation.
conclusionNeonatal/infant mortality in multiple births is still significantly high, which is mainly related with preterm birth. Close fetal monitoring is needed to prevent fetal death in triplet pregnancies, after 32 gestational weeks.
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