SynthesisPloS one2018
Prognostic factors for return to work and work disability among colorectal cancer survivors; A systematic review.
Synthesis in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 5 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- The unmet rehabilitation needs of colorectal cancer survivors after surgery: A qualitative meta-synthesis.Nursing open · 2024Pooled it
- Risk of mortality in COVID-19 patients: a meta- and network analysis.Scientific reports · 2023Pooled it
- Long-term work retention after treatment for cancer: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2020Pooled it
- Inflammatory biomarkers in patients with sciatica: a systematic review.BMC musculoskeletal disorders · 2019Pooled it
- Interventions to support return to work for people with coronary heart disease.The Cochrane database of systematic reviews · 2019Pooled it
- Social inequalities in return-to-work among colorectal cancer survivors in Germany.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Factors associated with long-term functional outcomes and participation in patients with colorectal cancers.Journal of rehabilitation medicine · 2026Article
- Multivariable prediction of returning to work among early-onset colorectal cancer survivors in China: A two-year follow-up.Asia-Pacific journal of oncology nursing · 2025Article
- Navigating work life after colorectal cancer: insights into work ability and functioning - a Danish follow-up study.Acta oncologica (Stockholm, Sweden) · 2025Article
- Employment status in cancer patients the first five years after diagnosis-a register-based study.Journal of cancer survivorship : research and practice · 2025Article
- Socioeconomic position and employment status in patients with lung cancer - a register-based study.Acta oncologica (Stockholm, Sweden) · 2025Article
- Long-term prescribed drug use in stage I-III rectal cancer patients in Sweden, with a focus on bowel-regulating drugs after surgical and oncological treatment.Journal of cancer survivorship : research and practice · 2025Article
- Experiences of work continuity among cancer survivors who are self-employed farmers.Journal of rural medicine : JRM · 2025Article
- Return to Work in Colorectal Cancer Patients.International journal of hematology-oncology and stem cell research · 2025Article
- Overall Observed Survival of Female Breast, Cervical, Colorectal, and Prostate Cancers in Antigua and Barbuda, 2017-2021: Retrospective Data from Four Study Sites.International journal of environmental research and public health · 2025Article
- Return to work in young and middle-aged colorectal cancer survivors: Factors influencing self-efficacy, fear, resilience, and financial toxicity.World journal of gastroenterology · 2025Article
- Article
- Article
- Measures of Work-life Balance and Interventions of Reasonable Accommodations for the Return to Work of Cancer Survivors: A Scoping Review.Safety and health at work · 2024Article
- Perioperative Rehabilitation in Collaboration with the Department of Occupational Medicine for Patients with Cholangiocarcinoma: A Case Report.Physical therapy research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColorectal cancer is diagnosed progressively in employed patients due to screening programs and increasing retirement age. The objective of this study was to identify prognostic factors for return to work and work disability in patients with colorectal cancer.
methodsThe research protocol was published at PROSPERO with registration number CRD42017049757. A systematic review of cohort and case-control studies in colorectal cancer patients above 18 years, who were employed when diagnosed, and who had a surgical resection with curative intent were included. The primary outcome was return to work or work disability. Potentially prognostic factors were included in the analysis if they were measured in at least three studies. Risk of bias was assessed according to the QUality In Prognosis Studies tool. A qualitative synthesis analysis was performed due to heterogeneity between studies. Quality of evidence was evaluated according to Grading of Recommendation Assessment, Development and Evaluation.
resultsEight studies were included with a follow-up period of 26 up to 520 weeks. (Neo)adjuvant therapy, higher age, and more comorbidities had a significant negative influence on return to work. A previous period of unemployment, extensive surgical resection and postoperative complications significantly increased the risk of work disability. The quality of evidence for these prognostic factors was considered very low to moderate.
conclusionHealth care professionals need to be aware of these prognostic factors to select patients eligible for timely intensified rehabilitation in order to optimize the return to work process and prevent work disability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.