GuidelineAmerican journal of respiratory and critical care medicine2018
Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.
Guideline in American journal of respiratory and critical care medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 195 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
195 citing papers in PubMed, 331 citations in OpenAlex.
- One-Year Echocardiographic, Functional, and Quality of Life Outcomes After Ultrasound-Facilitated Catheter-Based Fibrinolysis for Pulmonary Embolism.Circulation. Cardiovascular interventions · 2020Trial
- Group 3 Pulmonary Hypertension: Mechanistic Insights, Clinical Challenges, and Evolving Therapies.Journal of clinical medicine · 2026Review
- Longitudinal progression of tissue remodeling in experimental pulmonary hypertension is accompanied by a continuously increasing re-expression of extra domain A-containing fibronectin.Histochemistry and cell biology · 2026Article
- Clinical Risk Assessment of Acute Intermediate-Risk Pulmonary Embolism Using Repeat Transthoracic Echocardiography.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Article
- Angiogenic Potential of Endothelial Cells in Response to the Stiffness and Anisotropy of Right Ventricle Mimetic Scaffolds.Bioengineering (Basel, Switzerland) · 2026Article
- Activation of α7nAChR prevents maladaptive right ventricular remodeling via inhibiting the recruitment of CCR2Respiratory research · 2026Article
- Knowledge Assessment on the Management of Acute Cor Pulmonale: An Interdisciplinary Survey Study.Journal of clinical medicine · 2026Article
- 3D echo derived right ventricular principal surface strain in pulmonary arterial hypertension.American journal of physiology. Heart and circulatory physiology · 2026Article
- Cardiomyocyte NLRP3 signaling in right heart failure is sexually dimorphic via estrogen receptor α.bioRxiv : the preprint server for biology · 2026Article
- TAPSE/PASP combined with IVC can identify poor prognosis in PAH patients with low and intermediate risk.Clinical rheumatology · 2026Article
- Knowledge Gaps and Controversies on Cardiopulmonary Exercise Testing in the Assessment of Pulmonary Vascular Disease: An Official Statement of the Pulmonary Vascular Research Institute Exercise and Right Ventricular Function Task Force.Pulmonary circulation · 2026Article
- Advanced right ventricular evaluation in pulmonary hypertension: the role of 3D echocardiography and strain analysis.European heart journal. Imaging methods and practice · 2026Article
- Association of Immunoglobulin E With Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.Pulmonary circulation · 2026Article
- Pulmonary pulsatility quantified by electrical impedance tomography in severe acute respiratory distress syndrome patients undergoing extracorporeal membrane oxygenation support.Annals of intensive care · 2026Article
- Beyond the right ventricle: assessment of the left ventricular function in pulmonary hypertension.Frontiers in medicine · 2026Review
- Review
- Beyond the left ventricle: modern echocardiographic assessment of right ventricular function in tricuspid regurgitation.Cardiovascular ultrasound · 2025Review
- Transthoracic echocardiography of left ventricular underfilling improves risk stratification in pulmonary arterial hypertension.Scientific reports · 2025Article
- Exercise-induced out-of-proportion increase in afterload and impaired right ventricular contractile reserve in HFpEF.ESC heart failure · 2025Article
135 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 10 institutions in 5 countries.
Funding
Abstract
backgroundRight ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short- and long-term outcomes. Although remarkable progress has been made in the understanding of RV function and failure since the meeting of the NIH Working Group on Cellular and Molecular Mechanisms of Right Heart Failure in 2005, significant gaps remain at many levels in the understanding of cellular and molecular mechanisms of RV responses to pressure and volume overload, in the validation of diagnostic modalities, and in the development of evidence-based therapies.
methodsA multidisciplinary working group of 20 international experts from the American Thoracic Society Assemblies on Pulmonary Circulation and Critical Care, as well as external content experts, reviewed the literature, identified important knowledge gaps, and provided recommendations.
resultsThis document reviews the knowledge in the field of RV failure, identifies and prioritizes the most pertinent research gaps, and provides a prioritized pathway for addressing these preclinical and clinical questions. The group identified knowledge gaps and research opportunities in three major topic areas: 1) optimizing the methodology to assess RV function in acute and chronic conditions in preclinical models, human studies, and clinical trials; 2) analyzing advanced RV hemodynamic parameters at rest and in response to exercise; and 3) deciphering the underlying molecular and pathogenic mechanisms of RV function and failure in diverse pulmonary hypertension syndromes.
conclusionsThis statement provides a roadmap to further advance the state of knowledge, with the ultimate goal of developing RV-targeted therapies for patients with RV failure of any etiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.