Evidence map›Paper›PMID 30109846›Full record

ReviewEcoSal Plus2018

An Introduction to the Structure and Function of the Catalytic Core Enzyme of

Catherine Sutherland, Katsuhiko S Murakami

Abstract readReview
In one paragraph

Review in EcoSal Plus, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Structures ofScience advances · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Transcription activation inEcoSal Plus · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Investigation of Multi-SubunitInternational journal of molecular sciences · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Catherine SutherlandDepartment of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, PA 16802.
Katsuhiko S MurakamiDepartment of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, PA 16802.
Pennsylvania State University · US

Funding

X-Ray Crystallographic Studies of Multi-Subunit Nucleic Acid PolymerasesR01GM087350 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MURAKAMI, KATSUHIKO · 2010 to 2018
$2.6M
NIGMS NIH HHS R01 GM087350
6 · The paper itself

Abstract

RNA polymerase (RNAP) is the essential enzyme responsible for transcribing genetic information stored in DNA to RNA. Understanding the structure and function of RNAP is important for those who study basic principles in gene expression, such as the mechanism of transcription and its regulation, as well as translational sciences such as antibiotic development. With over a half-century of investigations, there is a wealth of information available on the structure and function of

Indexed as

Catalytic DomainCrystallography, X-RayDNADNA-Directed RNA PolymerasesEscherichia coliModels, MolecularProtein ConformationRNADNADNA-Directed RNA PolymerasesRNA

Identifiers

PMID30109846
PMCPMC6095464
OpenAlexW2886760740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.