Evidence map›Paper›PMID 30109826›Full record

ReviewPhysiology (Bethesda, Md.)2018

Physiological Consequences of Coronary Arteriolar Dysfunction and Its Influence on Cardiovascular Disease.

Hassan Allaqaband, David D Gutterman, Andrew O Kadlec

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Differential responses of resistance arterioles to elevated intraluminal pressure in blacks and whites.American journal of physiology. Heart and circulatory physiology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hassan AllaqabandCardiovascular Center, Medical College of Wisconsin , Milwaukee, Wisconsin.
David D GuttermanCardiovascular Center, Medical College of Wisconsin , Milwaukee, Wisconsin.ORCID 0000-0003-2814-7867
Andrew O KadlecCardiovascular Center, Medical College of Wisconsin , Milwaukee, Wisconsin.ORCID 0000-0003-2263-8622

Funding

Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7M
Novel Regulatory Mechanisms in the Human MicrocirculationR01HL135901 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI GUTTERMAN, DAVID D. · 2017 to 2020
$1.7M
NHLBI NIH HHS R01 HL135901NIGMS NIH HHS T32 GM080202
6 · The paper itself

Abstract

To date, the major focus of diagnostic modalities and interventions to treat coronary artery disease has been the large epicardial vessels. Despite substantial data showing that microcirculatory dysfunction is a strong predictor of future adverse cardiovascular events, very little research has gone into developing techniques for in vivo diagnosis and therapeutic interventions to improve microcirculatory function. In this review, we will discuss the pathophysiology of coronary arteriolar dysfunction, define its prognostic implications, evaluate the diagnostic modalities available, and provide speculation on current and potential therapeutic opportunities.

Indexed as

AnimalsArteriolesCardiovascular DiseasesCoronary Artery DiseaseHumansMicrocirculationMicrovesselsPrognosis

Identifiers

PMID30109826
PMCPMC6230549

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.