ArticleJournal of neurology2018
Clinical, imaging, and histological presentations and outcomes of stroke related to sarcoidosis.
Article in Journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Cerebral vasculitis related to neurosarcoidosis: a case series and systematic literature review.Journal of neurology · 2025Pooled it
- Recurrent Hemorrhagic Stroke in a Patient with Neurosarcoidosis.Internal medicine (Tokyo, Japan) · 2026Article
- Cerebrovascular Manifestations of Neurosarcoidosis - An Overview.Vascular health and risk management · 2026Review
- Neurosarcoidosis in Critical Care, Internal, and Pulmonary Medicine: A Practical Approach.Seminars in respiratory and critical care medicine · 2025Review
- Acute Ischemic Stroke in the Setting of Neurosarcoidosis.Clinical case reports · 2025Article
- Pediatric Meningeal Diseases: What Radiologists Need to Know.Tomography (Ann Arbor, Mich.) · 2024Review
- Neurosarcoidosis.Journal of neurology · 2024Article
- Pachymeningitis in Biopsy-Proven Sarcoidosis: Clinical Course, Radiographic Findings, Response to Treatment, and Long-term Outcomes.Neurology(R) neuroimmunology & neuroinflammation · 2022Article
- Cardioembolic Stroke Due to Cardiac Sarcoidosis Diagnosed by Pathological Evaluation of the Retrieved Thrombus.Internal medicine (Tokyo, Japan) · 2022Article
- A Case of Neurosarcoid Presenting as Multiple Intraparenchymal Hemorrhages.The Neurohospitalist · 2022Article
- Images of the month 1: Trident sign and neurosarcoidosis.Clinical medicine (London, England) · 2021Article
- How to Tackle the Diagnosis and Treatment in the Diverse Scenarios of Extrapulmonary Sarcoidosis.Advances in therapy · 2021Review
- Neurosarcoidosis with hydrocephalus as a first presenting sign: a unique case report.Clinical case reports · 2021Article
- Review
- Acute central nervous system vasculitis as a manifestation of neurosarcoidosis: A case report and literature review.Radiology case reports · 2021Article
- Clinical and MRI phenotypes of sarcoidosis-associated myelopathy.Neurology(R) neuroimmunology & neuroinflammation · 2020Article
- Intracranial calcifications on CT: an updated review.Journal of radiology case reports · 2019Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesClinical involvement of the nervous system is uncommon during sarcoidosis. Cerebrovascular events are rarely reported during sarcoidosis and may be confused with primary angiitis of the central nervous system. The characteristics and outcomes of cerebrovascular events during sarcoidosis have not been well-evaluated. PATIENTS AND
methodsWe conducted a retrospective case series in our institution with an updated review of the literature from 1962 to 2017 to characterize the clinical presentation, imaging, histology and outcomes of stroke that were thought to be causally related to sarcoidosis.
resultsFifty-one patients (31 men, median age at stroke diagnosis of 41 years) receiving a diagnosis of stroke and sarcoidosis, including 8 new cases from our institution and 43 from the literature review, were included. Stroke was the first manifestation of sarcoidosis in 64%. The stroke was ischemic in 69% and hemorrhagic in 31%. A total of 31% experienced a transient ischemic attack before ischemic stroke. A total of 36% of patients had multiple infarcts or hemorrhages. The median number of cardiovascular risk factors was 0. Concerning histological presentation, vascular or perivascular involvement was present in all cases. After a median follow-up of 12 months (after stroke), up to 50% of patients had developed a permanent neurological impairment, 16% had a recurrence of stroke, and 23% died.
conclusionsCerebrovascular events may be the first manifestation of neurosarcoidosis, and have a prognosis impact in such patients, leading to death and permanent neurological impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.