ArticleOpen forum infectious diseases2018
Increasing Rates of Invasive Group A Streptococcal Disease in Alberta, Canada; 2003-2017.
Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Infectious Diseases Among People Experiencing Homelessness: A Systematic Review of the Literature in the United States and Canada, 2003-2022.Public health reports (Washington, D.C. : 1974)Pooled it
- Invasive Group A Streptococcal Disease in Persons Experiencing Postpandemic Homelessness in Canada.JAMA network open · 2026Article
- Risk and determinants of mortality associated with invasive group A streptococcus (iGAS) disease in Scotland: A national surveillance study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025Article
- Group A Streptococcus among American Indian Persons, White Mountain Apache Tribal Lands, United States, 2016-2019Emerging infectious diseases · 2025Article
- Molecular and Clinical Characterization of InvasivePathogens (Basel, Switzerland) · 2025Article
- Global spread of Streptococcus pyogenes A genomics-supported narrative review.FEMS microbiology reviews · 2025Review
- Group A streptococcal infections in Alberta, Canada 2018-2023.Epidemiology and infection · 2024Article
- Invasive group A Streptococcus infection (Streptococcus pyogenes): Current situation in Spain.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024Article
- Strep A: challenges, opportunities, vaccine-based solutions, and economics.NPJ vaccines · 2024Review
- Increase in invasive group A streptococcal disease among Australian children coinciding with northern hemisphere surges.The Lancet regional health. Western Pacific · 2023Article
- Invasive group A streptococcal (iGAS) surveillance in Island Health, British Columbia, 2022.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023Article
- Group A Streptococcus Infections: Their Mechanisms, Epidemiology, and Current Scope of Vaccines.Cureus · 2022Review
- Increasing Incidence of Invasive Group A Streptococcus Disease, Idaho, USA, 2008-2019.Emerging infectious diseases · 2022Article
- Acute Rheumatic Fever and Rheumatic Heart Disease: Highlighting the Role of Group A Streptococcus in the Global Burden of Cardiovascular Disease.Pathogens (Basel, Switzerland) · 2022Review
- Case Report: Therapeutic Strategy With Delayed Debridement for Culture-Negative Invasive Group A Streptococcal Infections Diagnosed by Metagenomic Next-Generation Sequencing.Frontiers in public health · 2022Article
- Invasive Group A Streptococcal Infections Among People Who Inject Drugs and People Experiencing Homelessness in the United States, 2010-2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Application of the random forest algorithm to Streptococcus pyogenes response regulator allele variation: from machine learning to evolutionary models.Scientific reports · 2021Article
- Native Human Antibody to Shr Promotes Mice Survival After Intraperitoneal Challenge With Invasive Group A Streptococcus.The Journal of infectious diseases · 2021Article
- Diverse disease processes of group ABMJ case reports · 2021Article
- A Review ofPathogens (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe present an analysis of increasing rates of invasive group A streptococci (iGAS) over a 15-year period in Alberta, Canada.
methodsFrom 2003 to 2017, the
resultsA total of 3551 cases of iGAS were identified in Alberta by isolation of a GAS isolate from a sterile site. The age-standardized incidence rates of iGAS increased from 4.24/100 000 in 2003 to 10.24 in 2017. Rates (SD) were highest in those age <1 (9.69) years and 60+ (11.15) years; 57.79% of the cases were male. Commonly identified risk factors included diabetes, hepatitis C, nonsurgical wounds, addiction, alcohol abuse, drug use, and homelessness. The overall age-standardized case fatality rate was 5.11%. The most common clinical presentation was septicemia/bacteremia (41.84%), followed by cellulitis (17.25%). The top 4
conclusionsThe incidence of iGAS disease in Alberta, Canada, has increased from 2003 to 2017. This increase has been driven not by a single
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.