Evidence map›Paper›PMID 30109189›Full record

ArticleActa pharmaceutica Sinica. B2018

Xia Lv, Shuguang Zhang, Huipeng Ma, Peipei Dong, Xiaodong Ma, Ming Xu, Yan Tian, Zeyao Tang, Jinyong Peng, Haibo Chen and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xia LvCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Shuguang ZhangXinglin College, Liaoning University of Traditional Chinese Medicine, Shenyang 110167, China.
Huipeng MaCollege of Medical Laboratory, Dalian Medical University, Dalian 116044, China.
Peipei DongCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Xiaodong MaCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Ming XuCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Yan TianCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Zeyao TangCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Jinyong PengCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Haibo ChenCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Jianbin ZhangCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Dalian Medical University · CNLiaoning University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microemulsions are promising drug delivery systems for the oral administration of poorly water-soluble drugs. However, the evolution of microemulsions in the gastrointestinal tract is still poorly characterized, especially the structural change of microemulsions under the effect of lipase and mucus. To better understand the fate of microemulsions in the gastrointestinal tract, we applied small-angle X-ray scattering (SAXS) and fluorescence resonance energy transfer (FRET) to monitor the structural change of microemulsions under the effect of lipolysis and mucus. First, the effect of lipolysis on microemulsions was studied by SAXS, which found the generation of liquid crystalline phases. Meanwhile, FRET spectra indicated micelles with smaller particle sizes were generated during lipolysis, which could be affected by CaCl

Indexed as

FRETLipolysisLiquid crystalline phaseMicroemulsionsMucusSAXS

Identifiers

PMID30109189
PMCPMC6089861
OpenAlexW2804928244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.