Evidence map›Paper›PMID 30109020›Full record

ReviewF1000Research2018

Current overview and treatment of mantle cell lymphoma.

Michael Schieber, Leo I Gordon, Reem Karmali

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 47 citations in OpenAlex.

  1. The Novel Immunocompetent Eµ-SOX11CCND1 Mouse Model Phenotypically and Molecularly Resembles Human Mantle Cell Lymphoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Tackling Mantle Cell Lymphoma in Europe.Healthcare (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Observational
  10. Review
  11. Article
  12. Article
  13. SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2021
    Article
  14. Article
  15. B Cell Lymphomas of the GI Tract.Current gastroenterology reports · 2021
    Review
  16. High-Risk Mantle Cell Lymphoma in the Era of Novel Agents.Current hematologic malignancy reports · 2021
    Review
  17. Article
  18. A Unique Case of Mantle Cell Lymphoma Masquerading as a Cecal Mass.Case reports in gastrointestinal medicine · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael SchieberRobert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-9994-8579
Leo I GordonRobert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
Reem KarmaliRobert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA.
Northwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma with historically poor long-term survival compared with other B-cell malignancies. Treatment strategies for this disease are variable and dependent on symptoms and patient fitness. Despite recent advances, MCL remains incurable and patients with high-risk disease have particularly poor outcomes. This review focuses on recent developments that enhance our understanding of the biology of MCL and new treatment approaches that have led to substantial improvements in clinical outcomes. We will outline induction immuno-chemotherapy and maintenance strategies in transplant-eligible patients. In addition, effective strategies for patients unfit for intensive induction will be discussed, with a particular focus on novel molecular therapies with activity in MCL. Lastly, a number of ongoing clinical trials will be presented; the data from these trials are anticipated to redefine standards of care in the near future.

Indexed as

HumansLymphoma, Mantle-CellPrognosisRecurrenceClinical trialsDiagnosisManagementMantle Cell LymphomaTreatment

Identifiers

PMID30109020
PMCPMC6069726
OpenAlexW2883296901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.