Evidence map›Paper›PMID 30109005›Full record

ArticleMedChemComm2018

Mercaptoacetate thioesters and their hydrolysate mercaptoacetic acids jointly inhibit metallo-β-lactamase L1.

Cheng Chen, Yang Xiang, Ya Liu, Xiangdong Hu, Ke-Wu Yang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedChemComm, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cheng ChenKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education , Innovation Laboratory of Chemical Biology , College of Chemistry and Materials Science , Northwest University , Xi'an 710127 , P. R. China . Email: kwyang@nwu.edu.cn.
Yang XiangKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education , Innovation Laboratory of Chemical Biology , College of Chemistry and Materials Science , Northwest University , Xi'an 710127 , P. R. China . Email: kwyang@nwu.edu.cn.
Ya LiuKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education , Innovation Laboratory of Chemical Biology , College of Chemistry and Materials Science , Northwest University , Xi'an 710127 , P. R. China . Email: kwyang@nwu.edu.cn.
Xiangdong HuKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education , Innovation Laboratory of Chemical Biology , College of Chemistry and Materials Science , Northwest University , Xi'an 710127 , P. R. China . Email: kwyang@nwu.edu.cn.ORCID 0000-0002-8644-6454
Ke-Wu YangKey Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education , Innovation Laboratory of Chemical Biology , College of Chemistry and Materials Science , Northwest University , Xi'an 710127 , P. R. China . Email: kwyang@nwu.edu.cn.ORCID 0000-0003-4263-7694
Ministry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 'superbug' infection caused by metallo-β-lactamases (MβLs) including L1 has grown into an emerging threat. To probe whether mercaptoacetate thioesters inhibiting L1 is a contribution of the thioester itself or its hydrolysate, ten mercaptoacetate thioesters

Identifiers

PMID30109005
PMCPMC6071727
OpenAlexW2804075476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.