Evidence map›Paper›PMID 30108937›Full record

ArticleMedChemComm2018

Design, synthesis and biological evaluation of novel 5-hydroxy-2-methyl-4

Yi-Bin Li, Wen Hou, Hui Lin, Ping-Hua Sun, Jing Lin, Wei-Min Chen

Abstract read
In one paragraph

Article in MedChemComm, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Bin LiCollege of Pharmacy , Jinan University , Guangzhou 510632 , P. R. China . Email: linjing_jnu@163.com ; Email: twmchen@jnu.edu.cn ; ; Tel: +86 20 8522 1367 ; Tel: +86 20 8522 4497.
Wen HouCollege of Pharmacy , Jinan University , Guangzhou 510632 , P. R. China . Email: linjing_jnu@163.com ; Email: twmchen@jnu.edu.cn ; ; Tel: +86 20 8522 1367 ; Tel: +86 20 8522 4497.ORCID 0000-0003-0310-3307
Hui LinCollege of Pharmacy , Jinan University , Guangzhou 510632 , P. R. China . Email: linjing_jnu@163.com ; Email: twmchen@jnu.edu.cn ; ; Tel: +86 20 8522 1367 ; Tel: +86 20 8522 4497.
Ping-Hua SunCollege of Pharmacy , Jinan University , Guangzhou 510632 , P. R. China . Email: linjing_jnu@163.com ; Email: twmchen@jnu.edu.cn ; ; Tel: +86 20 8522 1367 ; Tel: +86 20 8522 4497.
Jing LinCollege of Pharmacy , Jinan University , Guangzhou 510632 , P. R. China . Email: linjing_jnu@163.com ; Email: twmchen@jnu.edu.cn ; ; Tel: +86 20 8522 1367 ; Tel: +86 20 8522 4497.ORCID 0000-0001-7707-8066
Wei-Min ChenCollege of Pharmacy , Jinan University , Guangzhou 510632 , P. R. China . Email: linjing_jnu@163.com ; Email: twmchen@jnu.edu.cn ; ; Tel: +86 20 8522 1367 ; Tel: +86 20 8522 4497.ORCID 0000-0002-0292-7841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

d-2-Hydroxyglutarate (d-2HG) is frequently found in human brain cancers. Approximately 50-80% of grade II glioma patients have a high level of d-2HG production, which can lead to cancer initiation. In this study, a series of novel 5-hydroxy-2-methyl-4

Identifiers

PMID30108937
PMCPMC6071749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.