Evidence map›Paper›PMID 30108916›Full record

ReviewMedChemComm2018

Applications and perspectives of nanomaterials in novel vaccine development.

Yingbin Shen, Tianyao Hao, Shiyi Ou, Churan Hu, Long Chen

Abstract readReview
In one paragraph

Review in MedChemComm, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
  4. Harnessing Nanocarriers to Advance Vaccine Development.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingbin ShenDepartment of Food Science and Engineering , School of Science and Engineering , Jinan University , Guangzhou 510632 , Guangdong , China . Email: shenybin412@gmail.com ; Email: daisyhallaiesec@gmail.com ; Email: tosy@jnu.edu.cn ; Email: hucr622@gmail.com ; Email: dexterchen@jnu.edu.cn ; ; Tel: +86 138 801 32918.ORCID 0000-0001-9767-1107
Tianyao HaoDepartment of Food Science and Engineering , School of Science and Engineering , Jinan University , Guangzhou 510632 , Guangdong , China . Email: shenybin412@gmail.com ; Email: daisyhallaiesec@gmail.com ; Email: tosy@jnu.edu.cn ; Email: hucr622@gmail.com ; Email: dexterchen@jnu.edu.cn ; ; Tel: +86 138 801 32918.
Shiyi OuDepartment of Food Science and Engineering , School of Science and Engineering , Jinan University , Guangzhou 510632 , Guangdong , China . Email: shenybin412@gmail.com ; Email: daisyhallaiesec@gmail.com ; Email: tosy@jnu.edu.cn ; Email: hucr622@gmail.com ; Email: dexterchen@jnu.edu.cn ; ; Tel: +86 138 801 32918.
Churan HuDepartment of Food Science and Engineering , School of Science and Engineering , Jinan University , Guangzhou 510632 , Guangdong , China . Email: shenybin412@gmail.com ; Email: daisyhallaiesec@gmail.com ; Email: tosy@jnu.edu.cn ; Email: hucr622@gmail.com ; Email: dexterchen@jnu.edu.cn ; ; Tel: +86 138 801 32918.
Long ChenDepartment of Food Science and Engineering , School of Science and Engineering , Jinan University , Guangzhou 510632 , Guangdong , China . Email: shenybin412@gmail.com ; Email: daisyhallaiesec@gmail.com ; Email: tosy@jnu.edu.cn ; Email: hucr622@gmail.com ; Email: dexterchen@jnu.edu.cn ; ; Tel: +86 138 801 32918.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines show great potential for both prophylactic and therapeutic use in infections, cancer, and other diseases. With the rapid development of bio-technologies and materials sciences, nanomaterials are playing essential roles in novel vaccine formulations and can boost antigen effectiveness by operating as delivery systems to enhance antigen processing and/or as immune-potentiating adjuvants to induce or potentiate immune responses. The effect of nanoparticles in vaccinology showed enhanced antigen stability and immunogenicity as well as targeted delivery and slow release. However, obstacles remain due to the lack of fundamental knowledge on the detailed molecular working mechanism and

Identifiers

PMID30108916
PMCPMC6083789

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.