Evidence map›Paper›PMID 30108865›Full record

ArticleMedChemComm2017

Synthesis of novel pentacyclic triterpene-Neu5Ac2en derivatives and investigation of their

Yongying Shi, Longlong Si, Xu Han, Zibo Fan, Shouxin Wang, Man Li, Jiaqi Sun, Yongmin Zhang, Demin Zhou, Sulong Xiao

Open access · greenAbstract read
In one paragraph

Article in MedChemComm, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 4 countries.

Yongying ShiState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Longlong SiState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Xu HanState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Zibo FanState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Shouxin WangState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Man LiState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Jiaqi SunState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Yongmin ZhangInstitut Parisien de Chimie Moléculaire , CNRS UMR 8232 , Sorbonne Universités , UPMC Univ Paris 06 , 4 place Jussieu , 75005 Paris , France.
Demin ZhouState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.
Sulong XiaoState Key Laboratory of Natural and Biomimetic Drugs , School of Pharmaceutical Sciences , Peking University , Beijing 100191 , China . Email: slxiao@bjmu.edu.cn.ORCID 0000-0002-6852-9504
Peking University · CNSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sialic acid derivatives, analogs, and their conjugates are important pharmacophores. Modification of the C-4 hydroxyl group of sialic acid can lead to derivatives, such as zanamivir, with potent anti-influenza activities. Herein, we described the synthesis of C-4-modified sialic acid derivatives

Identifiers

PMID30108865
PMCPMC6072002
OpenAlexW2621024189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.