Evidence map›Paper›PMID 30108842›Full record

ArticleMedChemComm2017

5-Methyl-

Li Wang, Ignacio Moraleda, Isabel Iriepa, Alejandro Romero, Francisco López-Muñoz, Mourad Chioua, Tsutomu Inokuchi, Manuela Bartolini, José Marco-Contelles

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedChemComm, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li WangDivision of Chemistry and Biotechnology , Graduate School of Natural Science and Technology , Okayama University , 3.1.1 Tsushima-Naka, Kita-ku , Okayama 700-8530 , Japan . Email: inokuchi@cc.okayama-u.ac.jp ; Tel: +81 86 294 5045.
Ignacio MoraledaDepartamento de Química Orgánica y Química Inorgánica , Universidad de Alcalá , Ctra. Madrid-Barcelona, Km. 33,6, 28871, Alcalá de Henares , Madrid , Spain.
Isabel IriepaDepartamento de Química Orgánica y Química Inorgánica , Universidad de Alcalá , Ctra. Madrid-Barcelona, Km. 33,6, 28871, Alcalá de Henares , Madrid , Spain.
Alejandro RomeroDepartamento de Toxicología y Farmacología , Facultad de Veterinaria , Universidad Complutense de Madrid , 28040-Madrid , Spain.
Francisco López-MuñozFaculty of Health , Camilo José Cela University , C/Castillo de Alarcón, 49; 28692 Villanueva de la Cañada , Madrid , Spain.
Mourad ChiouaLaboratory of Medicinal Chemistry (IQOG, CSIC) , C/ Juan de la Cierva 3 , 28006-Madrid , Spain . Email: iqoc21@iqog.csic.es ; Tel: +34 91 5622900.
Tsutomu InokuchiDivision of Chemistry and Biotechnology , Graduate School of Natural Science and Technology , Okayama University , 3.1.1 Tsushima-Naka, Kita-ku , Okayama 700-8530 , Japan . Email: inokuchi@cc.okayama-u.ac.jp ; Tel: +81 86 294 5045.
Manuela BartoliniDepartment of Pharmacy and Biotechnology , Alma Mater Studiorum , University of Bologna , Via Belmeloro 6 , 40126 Bologna , Italy . Email: manuela.bartolini3@unibo.it ; Tel: +39 0512099729.
José Marco-ContellesLaboratory of Medicinal Chemistry (IQOG, CSIC) , C/ Juan de la Cierva 3 , 28006-Madrid , Spain . Email: iqoc21@iqog.csic.es ; Tel: +34 91 5622900.ORCID 0000-0003-0690-0328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis, cholinesterase inhibition, molecular modelling and ADME properties of novel tacrine-neocryptolepine heterodimers are described. Compound

Identifiers

PMID30108842
PMCPMC6071787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.