Evidence map›Paper›PMID 30108771›Full record

ArticleMedChemComm2017

Shaun C Offerman, Manikandan Kadirvel, Osama H Abusara, Jennifer L Bryant, Brian A Telfer, Gavin Brown, Sally Freeman, Anne White, Kaye J Williams, Harmesh S Aojula

Open access · hybridAbstract read
In one paragraph

Article in MedChemComm, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. De Novo Discovery of Prenylated Macrocyclic Peptide Ligands.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
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  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 4 countries.

Shaun C OffermanDivision of Pharmacy and Optometry , School of Health Sciences , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK . Email: Harmesh.aojula@manchester.ac.uk.ORCID 0000-0002-2610-7469
Manikandan KadirvelCRUK-EPSRC Cancer Imaging Centre in Cambridge and Manchester , Manchester , M20 3LJ , UK.
Osama H AbusaraDivision of Pharmacy and Optometry , School of Health Sciences , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK . Email: Harmesh.aojula@manchester.ac.uk.ORCID 0000-0002-0856-5618
Jennifer L BryantDivision of Pharmacy and Optometry , School of Health Sciences , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK . Email: Harmesh.aojula@manchester.ac.uk.
Brian A TelferDivision of Pharmacy and Optometry , School of Health Sciences , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK . Email: Harmesh.aojula@manchester.ac.uk.
Gavin BrownCRUK-EPSRC Cancer Imaging Centre in Cambridge and Manchester , Manchester , M20 3LJ , UK.
Sally FreemanDivision of Pharmacy and Optometry , School of Health Sciences , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK . Email: Harmesh.aojula@manchester.ac.uk.
Anne WhiteDivision of Diabetes, Endocrinology & Gastroenterology , School of Medical Sciences , Faculty of Biology, Medicine, & Health , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK.
Kaye J WilliamsDivision of Pharmacy and Optometry , School of Health Sciences , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK . Email: Harmesh.aojula@manchester.ac.uk.
Harmesh S AojulaDivision of Pharmacy and Optometry , School of Health Sciences , Manchester Academic Health Sciences Centre , University of Manchester , Manchester , M13 9PL , UK . Email: Harmesh.aojula@manchester.ac.uk.ORCID 0000-0002-6266-3147
Manchester Academic Health Science Centre · GBEngineering and Physical Sciences Research Council · GB

Funding

Cancer Research UK 22805Medical Research Council MC_PC_13070
6 · The paper itself

Abstract

Natural prenylated indoles have been proposed as potential anticancer agents. To exploit this discovery for developing new peptide therapeutics, we report the first studies whereby incorporation of prenylated indoles into primary sequences has been achieved. We developed a route to synthesise N

Identifiers

PMID30108771
PMCPMC6072501
OpenAlexW2587873904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.