Evidence map›Paper›PMID 30108589›Full record

ArticleFrontiers in immunology2018

Antitumor Activity of Extract From the Sporoderm-Breaking Spore of

Jiyan Su, Lu Su, Dan Li, Ou Shuai, Yifan Zhang, Huijia Liang, Chunwei Jiao, Zhanchi Xu, Yong Lai, Yizhen Xie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Dynamic biomarkers indicate the immunological benefits provided by Ganoderma spore powder in post-operative breast and lung cancer patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Trial
  3. Article
  4. Potential Active Compounds ofFood science & nutrition · 2025
    Review
  5. Recent Advances in the Use ofPharmaceutics · 2025
    Review
  6. Developmental and reproductive toxicity assessment of sporoderm-removedFrontiers in cell and developmental biology · 2025
    Article
  7. Review
  8. Frontiers in immunology · 2025
    Article
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  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jiyan SuState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou, China.
Lu SuSchool of Pharmacy and Chemistry, Dali University, Dali, China.
Dan LiGuangdong Yuewei Edible Fungi Technology Co. Ltd., Guangzhou, China.
Ou ShuaiGuangdong Yuewei Edible Fungi Technology Co. Ltd., Guangzhou, China.
Yifan ZhangState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou, China.
Huijia LiangGuangdong Yuewei Edible Fungi Technology Co. Ltd., Guangzhou, China.
Chunwei JiaoGuangdong Yuewei Edible Fungi Technology Co. Ltd., Guangzhou, China.
Zhanchi XuSchool of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yong LaiSchool of Pharmacy and Chemistry, Dali University, Dali, China.
Yizhen XieState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou, China.
Dali University · CNGuangdong Academy of Sciences · CNGuangzhou University of Chinese Medicine · CNInstitute of Microbiology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As breast cancer is the leading cause of cancer-related deaths in women population worldwide, ongoing endeavor has been made for alternative regimens with improved efficacy but fewer adverse effects. Recently, active components from the spores of

Indexed as

AnimalsBacteriaBiological ProductsCell Line, TumorCTLA-4 AntigenFemaleGastrointestinal MicrobiomeMammary Neoplasms, ExperimentalMice, Inbred BALB CProgrammed Cell Death 1 ReceptorReishiRNA, Ribosomal, 16SSpores, FungalT-Lymphocytes, CytotoxicTumor BurdenBiological ProductsCTLA-4 AntigenProgrammed Cell Death 1 ReceptorRNA, Ribosomal, 16Scytotoxic T cellsexhaustiongut microbiotaimmune checkpointsspore of Ganoderma lucidum

Identifiers

PMID30108589
PMCPMC6079217
OpenAlexW2887195185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.