ReviewFrontiers in endocrinology2018
Biomarkers for Macrosomia Prediction in Pregnancies Affected by Diabetes.
Review in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Relationship Between Improvements in Glycemic Control and Risk of Pregnancy Complications in Patients With Diabetes Mellitus: Metaregression Analysis of Randomized Controlled Trials of Intensive Glucose Management.Journal of diabetes research · 2025Pooled it
- Human Placental Lactogen in Relation to Maternal Metabolic Health and Fetal Outcomes: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2022Pooled it
- Adverse birth outcome and associated factors among diabetic pregnant women in Ethiopia: Systematic review and meta-analysis.PloS one · 2020Pooled it
- Metabolic associations of human placental lactogen in pregnancies at high metabolic risk: An observational cohort study.Acta obstetricia et gynecologica Scandinavica · 2025Observational
- Association of the triglyceride-glucose index and the ratio of triglyceride to high-density lipoprotein cholesterol with fetal macrosomia in nulliparous pregnant women: a prospective case-control study.BMC pregnancy and childbirth · 2025Article
- Insulin-Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes.Journal of diabetes research · 2025Review
- Gestational diabetes mellitus in previous pregnancy associated with the risk of large for gestational age and macrosomia in the second pregnancy.Frontiers in endocrinology · 2025Article
- Can aspartate aminotransferase and platelet distribution width-to-platelet ratio in the first trimester predict fetal macrosomia?: a retrospective case-control study.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Unveiling Macrosomia Risks of Non-Diabetic Women: Insights from Second Trimester Maternal Lipid Profiles.Archives of Iranian medicine · 2024Article
- Association between infant birth weight and gestational weight gain in Japanese women with diabetes mellitus.Journal of diabetes investigation · 2024Article
- Metabolomics Signature in Prediabetes and Diabetes: Insights From Tandem Mass Spectrometry Analysis.Endocrinology, diabetes & metabolism · 2024Article
- Lipid profile in women of different ethnicity with gestational diabetes: Relationship with fetal growth.Journal of diabetes investigation · 2024Article
- Maternal fibrinogen/fibrin degradation products to high density lipoprotein cholesterol ratio for predicting delivery of small and large for gestational age infants: a pilot study.Lipids in health and disease · 2023Article
- The Effect of Maternal Race, Ethnicity, and Nativity on Macrosomia Among Infants Born in the United States.Cureus · 2023Article
- Article
- Does the Change in the Diagnostic Criteria for Gestational Diabetes in Poland Affect Maternal and Fetal Complications? A Prospective Study.Medicina (Kaunas, Lithuania) · 2022Article
- Lactogenic hormones in relation to maternal metabolic health in pregnancy and postpartum: protocol for a systematic review.BMJ open · 2022Article
- The Role of Slit-2 in Gestational Diabetes Mellitus and Its Effect on Pregnancy Outcome.Frontiers in endocrinology · 2022Article
- Investigation and Application of Risk Factors of Macrosomia Based on 10,396 Chinese Pregnant Women.Frontiers in endocrinology · 2022Article
- Development and validation of a new predictive model for macrosomia at late-term pregnancy: A prospective study.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large birthweight, or macrosomia, is one of the commonest complications for pregnancies affected by diabetes. As macrosomia is associated with an increased risk of a number of adverse outcomes for both the mother and offspring, accurate antenatal prediction of fetal macrosomia could be beneficial in guiding appropriate models of care and interventions that may avoid or reduce these associated risks. However, current prediction strategies which include physical examination and ultrasound assessment, are imprecise. Biomarkers are proving useful in various specialties and may offer a new avenue for improved prediction of macrosomia. Prime biomarker candidates in pregnancies with diabetes include maternal glycaemic markers (glucose, 1,5-anhydroglucitol, glycosylated hemoglobin) and hormones proposed implicated in placental nutrient transfer (adiponectin and insulin-like growth factor-1). There is some support for an association of these biomarkers with birthweight and/or macrosomia, although current evidence in this emerging field is still limited. Thus, although biomarkers hold promise, further investigation is needed to elucidate the potential clinical utility of biomarkers for macrosomia prediction for pregnancies affected by diabetes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.