Evidence map›Paper›PMID 30108509›Full record

ArticleFrontiers in physiology2018

Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer.

Iddrisu B Yabasin, Jaceline G P Sanches, Mohammed M Ibrahim, Jin Huidan, Walana Williams, Zhi-Li Lu, Qingping Wen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Iddrisu B YabasinDepartment of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jaceline G P SanchesDepartment of Pathology and Forensics, Dalian Medical University, Dalian, China.
Mohammed M IbrahimDepartment of Pathology and Forensics, Dalian Medical University, Dalian, China.
Jin HuidanDepartment of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Walana WilliamsDepartment of Microbiology and Immunology, Dalian Medical University, Dalian, China.
Zhi-Li LuDepartment of Ophthalmology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Qingping WenDepartment of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Dalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is reported to be the third and fourth, most diagnosed and cause of cancer associated deaths respectively. In 2012 for instance, about 1.4 million new cases were reported, and approximately 700,000 deaths recorded. Survival from CRC is dependent on the stage at which it is diagnosed coupled with appropriate surgical and medical intervention. Cisatracurium is widely used for skeletal muscle relaxation during abdominal surgeries, including bowel and colon surgeries. Recent studies reported that cisatracurium inhibits progression of human cancer cells, however, the mechanisms leading to the inhibition are yet to be completely understood. To elucidate mechanisms resulting particularly in tumor cell growth and metastasis, we developed

Indexed as

cisatracuriumcolorectal cancerinvasionmigrationp53

Identifiers

PMID30108509
PMCPMC6079220
OpenAlexW2887432749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.