Evidence map›Paper›PMID 30108474›Full record

ArticleFrontiers in neuroscience2018

Visualization of the Membranous Labyrinth and Nerve Fiber Pathways in Human and Animal Inner Ears Using MicroCT Imaging.

Rudolf Glueckert, Lejo Johnson Chacko, Dominik Schmidbauer, Thomas Potrusil, Elisabeth J Pechriggl, Romed Hoermann, Erich Brenner, Alen Reka, Anneliese Schrott-Fischer, Stephan Handschuh

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Article
  3. Volume rendering technique and high-resolution microCT: 3D exploration of the cochlear anatomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  4. The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Next Challenges of Vestibular Implantation in Humans.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Light sheet microscopy of the gerbil cochlea.The Journal of comparative neurology · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rudolf GlueckertDepartment of Otolaryngology, Medical University of Innsbruck, Innsbruck, Austria.
Lejo Johnson ChackoDepartment of Otolaryngology, Medical University of Innsbruck, Innsbruck, Austria.
Dominik SchmidbauerDepartment of Otolaryngology, Medical University of Innsbruck, Innsbruck, Austria.
Thomas PotrusilDepartment of Otolaryngology, Medical University of Innsbruck, Innsbruck, Austria.
Elisabeth J PechrigglDepartment of Anatomy, Histology and Embryology, Division of Clinical and Functional Anatomy, Medical University of Innsbruck, Innsbruck, Austria.
Romed HoermannDepartment of Anatomy, Histology and Embryology, Division of Clinical and Functional Anatomy, Medical University of Innsbruck, Innsbruck, Austria.
Erich BrennerDepartment of Anatomy, Histology and Embryology, Division of Clinical and Functional Anatomy, Medical University of Innsbruck, Innsbruck, Austria.
Alen RekaDepartment of Otolaryngology, Medical University of Innsbruck, Innsbruck, Austria.
Anneliese Schrott-FischerDepartment of Otolaryngology, Medical University of Innsbruck, Innsbruck, Austria.
Stephan HandschuhVetImaging, VetCore Facility for Research, University of Veterinary Medicine, Vienna, Austria.
Innsbruck Medical University · ATUniversität Innsbruck · ATUniversity of Veterinary Medicine Vienna · AT

Funding

Austrian Science Fund FWF I 3154
6 · The paper itself

Abstract

Design and implantation of bionic implants for restoring impaired hair cell function relies on accurate knowledge about the microanatomy and nerve fiber pathways of the human inner ear and its variation. Non-destructive isotropic imaging of soft tissues of the inner ear with lab-based microscopic X-ray computed tomography (microCT) offers high resolution but requires contrast enhancement using compounds with high X-ray attenuation. We evaluated different contrast enhancement techniques in mice, cat, and human temporal bones to differentially visualize the membranous labyrinth, sensory epithelia, and their innervating nerves together with the facial nerve and middle ear. Lugol's iodine potassium iodine (I

Indexed as

endolymphinner ear implantsmembranous labyrinthmicroanatomymicroCTnerve fiber trackingnon-destructive imagingperilymph

Identifiers

PMID30108474
PMCPMC6079228
OpenAlexW2885273358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.