Evidence map›Paper›PMID 30108459›Full record

ArticleDose-response : a publication of International Hormesis Society

Dose-Dependent Antifibrotic Effect of Chrysin on Regression of Liver Fibrosis: The Role in Extracellular Matrix Remodeling.

Cornel Balta, Alina Ciceu, Hildegard Herman, Marcel Rosu, Oana Maria Boldura, Anca Hermenean

Open access · goldAbstract read
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cornel BaltaInstitute of Life Sciences, "Vasile Goldis" Western University of Arad, Arad, Romania.
Alina CiceuInstitute of Life Sciences, "Vasile Goldis" Western University of Arad, Arad, Romania.
Hildegard HermanInstitute of Life Sciences, "Vasile Goldis" Western University of Arad, Arad, Romania.ORCID 0000-0002-6741-0245
Marcel RosuInstitute of Life Sciences, "Vasile Goldis" Western University of Arad, Arad, Romania.
Oana Maria BolduraDepartment of Chemistry, Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Banat University of Agricultural Sciences and Veterinary Medicine "King Mihai I of Romania," Timisoara, Romania.
Anca HermeneanInstitute of Life Sciences, "Vasile Goldis" Western University of Arad, Arad, Romania.
Vasile Goldis Western University of Arad · ROUnivesity of Life Science "King Mihai I" from Timisoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver fibrosis represents an overaccumulation of extracellular matrix (ECM). This study was designed to investigate the effect of chrysin on established ECM overproduction in carbon tetrachloride (CCl

Indexed as

chrysincollagenECMliver fibrosisMMPsTIMP-1

Identifiers

PMID30108459
PMCPMC6083810
OpenAlexW2886117604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.